Results 81 to 90 of about 57,027 (223)
Table S1. Control Insertions - Primary Medulloblastoma. Table S2. Control Insertions - Primary Medulloblastoma (per sample). Table S3. Foretinib Specific Insertions - Primary Medulloblastoma. Table S4.
Patryk Skowron (3954164) +10 more
core +1 more source
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Tissue Mechanics Govern Tumor Quiescence and Chemosensitivity in Medulloblastoma
Medulloblastoma is the most prevalent malignant brain tumor in children (WHO grade 4) that encompasses a heterogeneous group of cerebellar or brainstem embryonal tumors.
Momin, Ali Arman
core +1 more source
C, Worster-Drought, W E, Dickson
openaire +2 more sources
CMB = Classic medulloblastoma, DMB = Desmoplastic/nodular medulloblastoma, AMB = Large-cell/anaplastic medulloblastoma, SHH = SHH pathway medulloblastoma, WNT = WNT pathway medulloblastoma, Non-SHH/WNT = Non-SHH/WNT pathway medulloblastoma.athose ...
Yong Ren (86476) +8 more
core +1 more source
Dynamic Proton arc therapy for paediatric parameningeal rhabdomyosarcoma
Abstract Background Parameningeal rhabdomyosarcomas (PM‐RMS) are pediatric tumors with a high risk of local failure and severe toxicity. Intensity modulated proton therapy (IMPT) offers improved healthy tissue sparing compared to conventional photon‐based radiotherapy, and proton arc therapy (PAT) might offer further improvement in healthy tissue ...
Andreas Havsgård Handeland +6 more
wiley +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song +9 more
wiley +1 more source
A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz +17 more
wiley +1 more source
Genomic Characterization of Medulloblastoma [PDF]
Medulloblastoma is the most common malignant pediatric brain tumour. Although survival rates have improved in recent years, long-term survivors exhibit a significantly diminished quality of life complicated by neurological, endocrine, intellectual, and ...
Northcott, Paul A.
core +1 more source

