Results 21 to 30 of about 6,236 (217)
Revista Brasileira de Reumatologia, 2016 Aim: Various mutations have been identified in the Mediterranean fever (MEFV) gene which is reported to be responsible from Familial Mediterranean fever (FMF).
Mustafa Ferhat Öksuz +7 more
doaj +2 more sources
Frontiers in GeneticsFamilial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder, particularly present in the Mediterranean populations, and associated with pathogenic variants in the MEFV gene.
José-Noel Ibrahim +2 more
exaly +3 more sources
Frequencies of the MEFV Gene Mutations in Azerbaijan [PDF]
Balkan Journal of Medical Genetics, 2021 Abstract The MEFV (familial Mediterranean fever gene) researches were performed in the population of the Republic of Azerbaijan in 2016–2021. Seven mutations of the MEFV gene were identified in heterozygous, homozygous and compound ...
Huseynova LS, Mammadova SN, Aliyeva KAA
openaire +5 more sources
Prevalence and significance of MEFV gene mutations in patients with sarcoidosis
Scandinavian Journal of Rheumatology, 2015 Sarcoidosis is a chronic granulomatous disease. Pyrin has anti-inflammatory activity in the regulation of inflammasomes and is encoded by the Mediterranean fever (MEFV) gene. MEFV gene mutations trigger the inflammatory cascade and cause familial Mediterranean fever (FMF).
Sever, F. +5 more
openaire +3 more sources
Dimethylaminoparthenolide (DMAPT) as an alternative approach for treatment of Familial Mediterranean Fever (FMF) [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Familial Mediterranean Fever (FMF) is a hereditary auto-inflammatory disorder that is caused by mutations in the Mediterranean fever (MEFV) gene and is associated with an increase in pro-inflammatory cytokines, such as interleukin-1β (IL-1β)
Ali Mosayebian +4 more
doaj +1 more source
Course of COVID-19 in patients carrying different MEFV mutations of familial Mediterranean fever
Medicine ScienceFamilial Mediterranean Fever (FMF) is a genetic auto-inflammatory disease. Mutations in the Mediterranean fever (MEFV) gene cause inappropriate immune system triggering, leading to inflammatory episodes in the peritoneum, pleura, and joints.
Bilgehan Demir, Dogu Karahan
doaj +2 more sources
Turkish Journal of Internal Medicine, 2021 The aim of this study is to investigate the differences between males and females in clinical findings, hereditary characteristics, treatment responses and pathogen Mediterranean fever (MEFV) gene phenotype frequencies in FMF patients.
Ayten Dinar, Koray Ayar
doaj +1 more source
The Role of NLRP1, AIM2 and MEFV Inflammasomes in the High-Intensity Interval Training of Individuals With Obesity. [PDF]
ImmunologyThis study shows that 8 weeks of high‐intensity interval training (HIIT) modulate inflammasome‐related gene expression in individuals with obesity. HIIT increased AIM2, MEFV, CARD16 and CARD18 expression, with CARD16 upregulation supporting reduced inflammation through inhibition of caspase‐1 activation and lower IL‐1β levels.
Silveira ALPA +8 more
europepmc +2 more sources
Analysis of the mutations in exon 10 of MEFV gene in patients with premature coronary heart disease in west Azerbaijan province of Iran [PDF]
Journal of Cardiovascular and Thoracic Research, 2018 Introduction: Premature coronary heart disease (PCHD) affects public health and leads to death. PCHD has several genetic and environmental risk factors. The aim of this study was to analysis of the mutations in exon 10 of MEFV gene in patients with PCHD ...
Morteza Bagheri +7 more
doaj +1 more source
MEFV mutations in Beh�et's disease [PDF]
Human Mutation, 2000 Familial Mediterranean fever (FMF) and Behçet's disease (BD), both inflammatory diseases, are highly prevalent in the Middle Eastern and Mediterranean populations. FMF is a Mendelian autosomic recessive disease linked to MEFV, a gene of unknown function.
I, Touitou +12 more
openaire +2 more sources