Frequencies of the MEFV Gene Mutations in Azerbaijan [PDF]
Balkan Journal of Medical Genetics, 2022 The MEFV (familial Mediterranean fever gene) researches were performed in the population of the Republic of Azerbaijan in 2016–2021. Seven mutations of the MEFV gene were identified in heterozygous, homozygous and compound homozygous conditions: R761H ...
Huseynova LS, Mammadova SN, Aliyeva KAA
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Recurrent synovitis of hip and MEFV gene related arthritis in children [PDF]
Pediatric Rheumatology Online Journal, 2020 Background Recurrent and relapsing arthritis has been proposed to describe a group of arthritis with recurring and periodic nature, in which the joints are intermittently involved.
Farhad Salehzadeh, Mehrdad Mirzarahimi
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Genetic and Epigenetic Regulation of MEFV Gene and Their Impact on Clinical Outcome in Auto-Inflammatory Familial Mediterranean Fever Patients [PDF]
Current Issues in Molecular Biology, 2023 Epigenetic modifications play a pivotal role in autoimmune/inflammatory disorders and could establish a bridge between personalized medicine and disease epidemiological contexts.
May E. Zekry +5 more
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Evaluation of the Clinical Effects and Frequency of MEFV Gene Mutation in Patients with Inflammatory Bowel Disease [PDF]
Gastroenterology Research and Practice, 2021 Background. The clinical and pathological features of inflammatory bowel disease (IBD) and Familial Mediterranean Fever (FMF) are similar. Objective. Here, the frequency of Mediterranean Fever (MEFV) gene mutation and its effect on the outcome of IBD ...
S. Sahin, D. Gulec, S. Günay, C. Cekic
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MEFV gene mutations in neuro‐Behçet's disease and neuro‐Sweet disease [PDF]
Annals of Clinical and Translational Neurology, 2019 Mediterranean fever (MEFV) gene mutations are associated with familial Mediterranean fever (FMF). Recent studies have suggested that MEFV gene mutations may act as disease modifiers in neuro‐Behçet's (NBD) disease and neuro‐Sweet disease (NSD).
Hidehiro Ishikawa +14 more
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A novel single variant in the MEFV gene causing Mediterranean fever and Behçet’s disease: a case report [PDF]
Journal of Medical Case Reports, 2018 Background Familial Mediterranean fever is an autoinflammatory disease of unknown etiology, characterized clinically by recurrent attacks of sudden-onset fever with arthralgia and/or thoracoabdominal pain and pathogenetically by autosomal recessive ...
Maria Zerkaoui +4 more
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The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis [PDF]
Pediatric Rheumatology Online Journal, 2020 Background Systemic juvenile idiopathic arthritis (sJIA) has many clinical features overlapping with familial Mediterranean fever (FMF), which is caused by mutations in MEFV gene. And FMF patients were easily misdiagnosed as sJIA in China.
Linqing Zhong +10 more
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Idiopathic CRMO and MEFV Gene Variant Alleles: Is There Any Relationship? [PDF]
Case Reports in Rheumatology, 2019 Background and Objective. CRMO is an inflammatory disease of bone that occurs more often in children. The clinical manifestations are intermittent fever, pain, and bone lesions, especially in long bones.
Farhad Salehzadeh +2 more
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Associations of MEFV gene variants, IL-33, and sST2 with the risk of Henoch-Schönlein purpura in children [PDF]
HeliyonObjective: Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children. HSP is a multifactorial inflammatory disease, but its pathogenesis is still unclear.
Yang Ruan, Longlong Xie
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Impact of Mediterranean Fever Gene Mutations on Clinical Characteristics in Patients With Inflammatory Bowel Disease [PDF]
Gastro Hep AdvancesBackground and Aims: The Mediterranean fever (MEFV) gene, which encodes a pyrin protein, is the causative gene of familial Mediterranean fever. Patients with inflammatory bowel disease (IBD) have a significantly higher frequency of MEFV mutations than ...
Tomoya Nakamura +10 more
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