Results 11 to 20 of about 6,862 (214)

MEFV gene mutation distrubution in Azerbaijan population [PDF]

Pediatr Rheumatol Online J, 2015
Familial Mediterranean fever (FMF)(MIM 249100) is a hereditary autoinflammatory disorder characterized by episodes of inflammation in the absence of high-titer autoantibodies or antigen-specific T cells. The Mediterranean fever (MEFV) gene(OMIM 608107) located on chromosome 16p13.3, which encodes the 781-amino-acid protein pyrin, is the causative gene ...
Berdeli A, Mukhtarova G, Oz A, Musayev S.   +3 more
europepmc   +4 more sources

Genetic Analysis of MEFV Gene Pyrin Domain in Patients With Behçet's Disease [PDF]

Mediators of Inflammation, 2006
Objectives. Behçet's disease (BD) is a systemic vasculitis with recurrent oral and genital ulcers and uveitis. MEFV gene, which is the main factor in familial Mediterranean fever (FMF), is also reported to be a susceptibility gene for BD.
Ahmet Dursun, Hatice Gul Durakbasi-Dursun, Ayse Gul Zamani, Zerrin Gülin Gulbahar, Recep Dursun, Cengiz Yakicier   +5 more
doaj   +7 more sources

Repeated Necrotizing Lymphadenitis with MEFV Gene Mutations. [PDF]

Intern Med, 2022
We herein report a 36-year-old man with repeated necrotizing lymphadenitis due to MEFV gene mutations. The patient's chief complaints were a fever and painful cervical lymphadenopathy. We diagnosed him with necrotizing lymphadenitis based on the pathological findings of the lymph nodes and the exclusion of other differential diseases.
Yamamura Y, Furuichi K, Toyama T, Oshima M, Ogura H, Sato K, Nakagawa S, Miyagawa T, Kitajima S, Hara A, Iwata Y, Sakai N, Shimizu M, Ikeda H, Toma T, Takasawa K, Yachie A, Wada T.   +17 more
europepmc   +3 more sources

Prediction of More Severe MEFV Gene Mutations in Childhood. [PDF]

Turk Arch Pediatr, 2021
This study aimed to present the demographic, clinical, and laboratory features of children clinically diagnosed with familial Mediterranean fever (FMF) and to predict more severe mutations by evaluating those findings.We enrolled cases diagnosed with FMF with a defined variation in at least one allele.
Güneş-Yılmaz S, Kasap-Demir B, Soyaltın E, Erfidan G, Özdemir-Şimşek Ö, Arslansoyu-Çamlar S, Alaygut D, Mutlubaş F.   +7 more
europepmc   +4 more sources

MEFV Gene Profile in Northwest of Iran, Twelve Common MEFV Gene Mutations Analysis in 216 Patients with Familial Mediterranean Fever

Iranian Journal of Medical Sciences, 2015
Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease with autosomal recessive inheritance pattern often seen around the Mediterranean Sea. It is characterized by recurrent episodes of fever and polyserositis and rash.
Farhad Salehzadeh, Mehdi Jafari Asl, Saeid Hosseini Asl, Sepideh Jahangiri, Shahram Habibzadeh   +4 more
doaj   +2 more sources

Immunogenic Potential of the Mediterranean Fever Gene in Patients with Coronavirus Disease: A Cross-Sectional Study [PDF]

Iranian Journal of Medical Sciences, 2023
Background: In December 2019, an outbreak of pneumonia caused by the novel coronavirus disease 2019 (COVID-19) became a pandemic and caused a global health crisis.
Farhad Salehzadeh, Farhad Pourfarzi, Rasool Molatefi, Behzad Davarnia, Ehsan Shahbazfar, Farzad Ahmadabadi   +5 more
doaj   +1 more source

MEFV gene variations in COVID-19 pneumonia patients (Pilot study). [PDF]

J Genet Eng Biotechnol
The emergence of worldwide pandemic caused by coronavirus 2 (SARS-CoV-2) has caused a radical change in everyday life. Patients diseased with FMF show manifestations and labs highly similar to COVID infected patients. In the current study, we evaluate the presence of variants in exon 10 of MEFV gene and the relation with severity of symptoms in ...
Radwan NA, Gohary HE, Hamed D, Khalil NM, Abdelfatah D, Wahab AA, Elsharkawy MM.   +6 more
europepmc   +4 more sources

Genewise detection of variants in MEFV gene using nanopore sequencing. [PDF]

Front Genet
Familial Mediterranean Fever (FMF) is a genetic disorder with complex inheritance patterns and genotype-phenotype associations, and it is highly prevalent in Armenia. FMF typically follows an autosomal recessive inheritance pattern (OMIM: 249100), though it can occasionally display a rare dominant inheritance pattern with variable penetrance (OMIM ...
Ghukasyan L, Khachatryan G, Sirunyan T, Minasyan A, Hakobyan S, Chavushyan A, Hayrapetyan V, Ghazaryan H, Martirosyan G, Mkrtchyan G, Vardanyan V, Mukuchyan V, Davidyants A, Zakharyan R, Arakelyan A.   +14 more
europepmc   +4 more sources

P01-004 – MEFV genes and FMF [PDF]

Pediatric Rheumatology, 2013
Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease with autosomal recessive inheritance pattern often seen in the Turks, Arabs, Armenians and Jews people characterised by recurrent episoded of fever and polyserositis and rash. Recently the definitive diagnosis of FMF determines by MEFV gene analysis.
Salehzadeh, F, Jafariasl, M, Jahangiri, S, Hosseiniasl, S   +3 more
openaire   +1 more source

P03-001 - PFAPA and MEFV genes [PDF]

Pediatric Rheumatology, 2013
Marshall Syndrome or PFAPA is an inflammatory periodic disease characterized by periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis. Restless, headache, abdominal pain, vomiting, hepatosplenomegaly and arthralgia are less common symptoms seeing in this disease.
Salehzadeh, F, Vahedi, M, Jahangiri, S, Hosseiniasl, S   +3 more
openaire   +1 more source