Results 71 to 80 of about 6,862 (214)

Mediterranean fever gene variants may prevent the development of lupus nephritis in Japanese patients with systemic lupus erythematosus

Frontiers in Immunology
BackgroundSystemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of immune tolerance, leading to systemic inflammation and organ damage. The Mediterranean fever (MEFV) gene, primarily linked to familial Mediterranean fever (FMF)
Yushiro Endo, Tomohiro Koga, Lamiaa Mohamed, Yoshika Tsuji, Masataka Umeda, Hiroko Hayashi, Tatsuya Kishino, Atsushi Kawakami   +7 more
doaj   +1 more source

Anesthesia experience along with familial Mediterranean fever and celiac disease [PDF]

, 2014
(Anesthetic management in patient with Familial Mediterranean Fever and Celiac Disease) Familial Mediterranean Fever is an autosomal recessive transmitted disease which often seen at Mediterranean origin society and it goes by deterioration at ...
Gülçin Hacıbeyoğlu, Hale Borazan, Mehmet Sargın, Şeref Otelcioğlu   +3 more
core   +1 more source

STING inhibition alleviates experimental peritoneal damage: potential therapeutic relevance for peritoneal dialysis

The Journal of Pathology, Volume 267, Issue 2, Page 196-212, October 2025.
Abstract Peritoneal dialysis (PD) is a widely used kidney replacement therapy for patients with end‐stage kidney disease. Nevertheless, long‐term exposure to PD fluid can damage the peritoneal membrane, leading to ultrafiltration failure and, ultimately, discontinuation of PD.
Vanessa Marchant, Jorge García‐Giménez, Guadalupe T González‐Mateo, Pilar Sandoval, Lucía Tejedor‐Santamaria, Sandra Rayego‐Mateos, Ricardo Ramos, José A Jiménez‐Heffernan, Alberto Ortiz, Anne‐Catherine Raby, Manuel López‐Cabrera, Adrián M Ramos, Marta Ruiz‐Ortega   +12 more
wiley   +1 more source

Analysis Of Mefv Gene Alternatively Spliced Transcripts Expression Patterns In Cell Culture Models [PDF]

, 2014
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2013Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2013Ailevi Akdeniz Ateşi (AAA), bölgemizdeki görülme sıklığı 1/200 ila 1/1073 arasında
Abacı, İrem
core  

IgA Vasculitis Across the Ages: Is It Time for a Precision Medicine Approach?

ACR Open Rheumatology, Volume 7, Issue 9, September 2025.
IgA vasculitis (IgAV; formerly Henoch‐Schönlein purpura) is a systemic small vessel vasculitis most commonly affecting the skin, gut, joints, and kidneys. Nephritis is the most concerning complication for all ages because it carries the risk of progression to irreversible end‐stage kidney failure.
A. Gage, R. J. Pepper, J. Marro, A. D. Salama, L. Oni   +4 more
wiley   +1 more source

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, Volume 12, Issue 34, September 11, 2025.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever

BMC Medical Genetics, 2011
Background MEFV mutations and decreased expression level of the gene are related to FMF pathology. DNA methylation at CpG islands is a well-known mechanism for transcriptional silencing.
Ozdogan Huri, Hatemi Gulen, Celikyapi Erdem Gokce, Arisoy Nil, Kasapcopur Ozgur, Kirectepe Asli K, Tahir Turanli Eda   +6 more
doaj   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, Volume 12, Issue 31, August 21, 2025.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source

Familial Mediterranean fever in Armenian children with inflammatory bowel disease

Frontiers in Pediatrics
Inflammatory bowel disease (IBD) and familial Mediterranean fever (FMF) are inflammatory diseases with complex interactions among genetic, immune, and environmental factors.
Gayane Amaryan, Gayane Amaryan, Tamara Sarkisian, Tamara Sarkisian, Artashes Tadevosyan, Christian Braegger   +5 more
doaj   +1 more source

Analysis of the genetic basis of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. [PDF]

, 2015
PFAPA syndrome is the most common autoinflammatory syndrome in children from Western countries. In spite of its strong familial clustering, its genetic basis and inheritance pattern are still unknown.
Bedoni, N., Gioia, S.A., Hofer, M., Rivolta, C., Superti-Furga, A., Vanoni, F., von Scheven-Gête, A.   +6 more
core   +3 more sources