Results 71 to 80 of about 2,516,978 (116)

MEFV gene variations in patients with systemic lupus erythematosus

, 2014
Objective The aim of this study was to investigate the frequency of familial Mediterranean fever (FMF)-associated MEFV gene variations in patients with systemic lupus erythematosus (SLE)
Ustek, Duran, Oku, Basar, Inanc, Murat, Gül, Ahmet, Aral, Orhan, Cosan, Fulya, Erer, Burak   +6 more
core   +1 more source

MEFV gene variation R202Q is associated with metabolic syndrome

, 2016
OBJECTIVE: MEFV (Mediterranean fever) gene encoding pyrin regulates inflammatory responses. It has been shown that MEFV gene variations are associated with higher acute phase responses and altered course in the different inflammatory diseases.
Akyol, M., Çobankara, Veli, Balkarli, A., Elmas, Levent, Tepeli, Emre   +4 more
core  

R202Q Mutation of Mediterranean Fever Gene in Iranian patients with Systemic-onset Juvenile Idiopathic Arthritis

Research in Molecular Medicine, 2014
Background: Systemic-onset Juvenile Idiopathic Arthritis (SoJIA) is an autoinflammatory disease with complex genetic trait starts in children less than 16 years of age with fever and cutaneous rash.
Shirin Farivar, Mahdieh Hasani, Reza Shiari   +2 more
doaj  

The MEFV gene pathogenic variants and phenotype-genotype correlation in children with familial Mediterranean fever in the Çanakkale population

Balkan Journal of Medical Genetics, 2016
The aim of the current study was to determine the frequency of the Mediterranean fever (MEFV) gene pathogenic variants in 60 children diagnosed with familial Mediterranean fever (FMF) and to compare the phenotype-genotype correlation.
Battal F, Silan F, Topaloğlu N, Aylanç H, Yıldırım Ş, Köksal Binnetoğlu F, Tekin M, Kaymaz N, Ozdemir O   +8 more
doaj   +1 more source

Involvement of Mediterranean fever gene mutations in colchicine-responsive enterocolitis: a retrospective cohort studyResearch in context

EBioMedicine
Summary: Background: The involvement of Mediterranean fever (MEFV) gene mutations in patients with inflammatory bowel disease unclassified (IBDU) remains unclear.
Hiroshi Nakase, Kohei Wagatsuma, Taku Kobayashi, Takayuki Matsumoto, Motohiro Esaki, Kenji Watanabe, Reiko Kunisaki, Teruyuki Takeda, Katsuhiro Arai, Takashi Ibuka, Dai Ishikawa, Yuichi Matsuno, Hirotake Sakuraba, Nobuhiro Ueno, Kaoru Yokoyama, Masayuki Saruta, Ryota Hokari, Junji Yokoyama, Shu Tamano, Masanori Nojima, Tadakazu Hisamatsu, Shusaku Yoshikawa, Sohachi Nanjo, Akira Andoh, Takeshi Kimura, Makoto Ooi, Ryosuke Kiyomori, Nobuo Aoyama, Fumihito Hirai, Atsushi Yamaushi, Masanao Nakamura, Fumikazu Koyama, Shuhei Hosomi, Kazuki Kakimoto, Satoshi Motoya, Ryosuke Sakemi, Hideo Suzuki, Tadashi Hosoya, Ken Takeuchi, Manabu Shiraki, Hideyuki Koide, Ichiro Takeuchi, Yosuke Furui, Kento Yoshida, Ayaka Minemura, Asami Matsumoto, Kentaro Oka   +46 more
doaj   +1 more source

The clinical significance of the Mediterranean fever gene MEFV variants in Castleman disease

Communications Medicine
Background Idiopathic Multicentric Castleman Disease, Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Organomegaly (iMCD-TAFRO) is a rare cytokine storm syndrome with high mortality.
Yumo Du, Shuangfeng Xie, Zhen Dai, Wenqi Jia, Wenjuan Li, Long Zhang, Guangzhou Du, Haijiao Zhang, Qiao Lin, Meiping Wu, Yiqing Li, Wenjuan Yang, Jie Xiao, Yongxun Zhuansun, Jianguo Li, Wenying Zhang, Shanping Jiang, Danian Nie, Kezhi Huang   +18 more
doaj   +1 more source

R202Q/M694V as novel MEFV gene mutations in chronic periodontitis and familial Mediterranean fever

, 2017
Background and Objective: Familial Mediterranean fever (FMF) and chronic periodontitis are inflammatory diseases leading to an increase in the number of inflammasomes.
Ö. Bağcı, H. Orhan, Ö. Fentoğlu, F. Y. Kırzıoğlu, Bagci, O., Fentoglu, O., G. Dinç, Dinc, G., Kirzioglu, F. Y., Ilhan, I., Orhan, H., İ. İlhan, A. Doğru, Dogru, A.   +13 more
core   +1 more source

Association between sequence variations of the Mediterranean fever gene and the risk of migraine: a case–control study

Neuropsychiatric Disease and Treatment, 2016
Salih Coşkun,1 Sefer Varol,2 Hasan H Özdemir,2 Sercan Bulut Çelik,3 Metin Balduz,4 Mehmet Akif Camkurt,5 Abdullah Çim,1 Demet Arslan,2 Mehmet Uğur Çevik2 1Department of Medical Genetics, 2Department of Neurology,
Coskun S, Varol S, Ozdemir HH, Bulut Celik S, Balduz M, camkurt MA, Cim A, Arslan D, Cevik MU   +8 more
doaj  

Familial Mediterranean Gene (MEFV) Mutation in Parents of Children with Familial Mediterranean Fever: What Are the Exceptions?

International Journal of Inflammation, 2018
Objectives. Familial Mediterranean Fever (FMF) is one of the most prevalent periodic fever syndromes; MEFV, the responsible gene for the disease, is in the short arm of chromosome16.
Leila Shahbaznejad, Sayed-Reza Raeeskarami, Raheleh Assari, Abbas Shakoori, Hamidreza Azhideh, Yahya Aghighi, Fatemeh Tahghighi, Vahid Ziaee   +7 more
doaj   +1 more source

1Novel MEFV transcripts in Familial Mediterranean fever patients and controls

BMC Medical Genetics, 2010
Background Familial Mediterranean fever is a recessive autoinflammatory disease frequently encountered in Armenians, Jews, Arabs and Turks. The MEFV gene is responsible for the disease. It encodes a protein called pyrin/marenostrin involved in the innate
Jalkh Nadine, Chouery Eliane, Nehme Nancy, Medlej-Hashim Myrna, Megarbane André   +4 more
doaj   +1 more source