Results 91 to 100 of about 1,294,883 (245)

Familial Mediterranean fever in Armenian children with inflammatory bowel disease

Frontiers in Pediatrics
Inflammatory bowel disease (IBD) and familial Mediterranean fever (FMF) are inflammatory diseases with complex interactions among genetic, immune, and environmental factors.
Gayane Amaryan, Gayane Amaryan, Tamara Sarkisian, Tamara Sarkisian, Artashes Tadevosyan, Christian Braegger   +5 more
doaj   +1 more source

Colitis in a patient with familial Mediterranean fever: Is it Crohn's disease or ulcerative colitis?

DEN Open, Volume 5, Issue 1, April 2025.
Abstract A 24‐year‐old woman was referred to our hospital with joint pain, fever, abdominal pain, and diarrhea. A colonoscopy revealed longitudinal ulcers with a cobblestone appearance throughout the entire colon, suggestive of Crohn's disease. However, treatment with 5‐aminosalicylic acid, azathioprine, and infliximab failed to achieve clinical ...
Ayano Hoshi, Yuichi Shimodate, Tatsuhiro Gotoda, Rio Takezawa, Naoyuki Nishimura, Hirokazu Mouri, Kazuhiro Matsueda, Motowo Mizuno, Takayuki Matsumoto   +8 more
wiley   +1 more source

R202Q Mutation of Mediterranean Fever Gene in Iranian patients with Systemic-onset Juvenile Idiopathic Arthritis

Research in Molecular Medicine, 2014
Background: Systemic-onset Juvenile Idiopathic Arthritis (SoJIA) is an autoinflammatory disease with complex genetic trait starts in children less than 16 years of age with fever and cutaneous rash.
Shirin Farivar, Mahdieh Hasani, Reza Shiari   +2 more
doaj  

Soluble Triggering Receptors on Myeloid Cells‐1 Could Be a Potential Biomarker for Disease Activity in Familial Mediterranean Fever

Journal of Clinical Laboratory Analysis, Volume 39, Issue 8, April 2025.
FMF is a common autoinflammatory disease, yet reliable biomarkers for distinguishing between attack and attack‐free periods remain limited. Our research demonstrates that sTREM‐1 levels are significantly elevated during FMF attacks compared with both attack‐free and control groups, suggesting its potential as a marker of inflammatory activity ...
Meryem Cemiloglu, Oguzhan Ozcan, Gezmis Kimyon, Abdullah Arpaci, Hamdi Oguzman   +4 more
wiley   +1 more source

Idiopathic CRMO and MEFV Gene Variant Alleles: Is There Any Relationship?

Case Reports in Rheumatology, 2019
Background and Objective. CRMO is an inflammatory disease of bone that occurs more often in children. The clinical manifestations are intermittent fever, pain, and bone lesions, especially in long bones.
Farhad Salehzadeh, Hassan Anari, Sepehr Sarkhanloo   +2 more
doaj   +1 more source

Supersulfides: A Promising Therapeutic Approach for Autoinflammatory Diseases

Microbiology and Immunology, Volume 69, Issue 4, Page 191-202, April 2025.
ABSTRACT Supersulfides are molecular species characterized by catenated sulfur moieties, including low‐molecular‐weight and protein‐bound supersulfides. Emerging evidence suggests that these molecules, abundantly present in diverse organisms, play essential roles far beyond their chemical properties, such as functions in energy metabolism, protein ...
Tianli Zhang, Touya Toyomoto, Tomohiro Sawa, Takaaki Akaike, Tetsuro Matsunaga   +4 more
wiley   +1 more source

A Proposed Classification of the Immunological Diseases [PDF]

, 2006
The formal recognition and genetic understanding of the autoinflammatory diseases has defined mechanisms of self-directed inflammation that are independent of adaptive ...
Burnet, Davidson, Dennis McGonagle, Dieterich, Ferguson, Ferguson, Galon, Gul, Hawkins, Hugot, Hull, Israeli, Lesage, Lodes, Mariathasan, Marrack, Martinon, Matzinger, Matzinger, McDermott, McDermott, McGonagle, McGonagle, McGonagle, McGonagle, Michael F McDermott, Ogura, Pascual, Ponticelli, Reimann, Rhodes, Rioux, Rose, Shi, Stojanov, Strober, Tan, Tan, Wucherpfennig   +38 more
core   +3 more sources

A Patient With Concurrent Hidradenitis Suppurativa and Porokeratosis Palmaris et Plantaris Disseminata: Case Report and Review of Autoinflammatory Keratinization Diseases

Journal of Cutaneous Pathology, Volume 52, Issue 4, Page 272-277, April 2025.
ABSTRACT The term autoinflammatory keratinization diseases (AIKDs) was recently proposed as a unifying concept for diseases characterized by inflammation in the epidermis and upper dermis which leads to hyperkeratosis, caused by genetic perturbations of the innate immune system.
Meredith C. Rogers, Mark Ash, Amanda Hernandez, Gregory A. Hosler   +3 more
wiley   +1 more source

MEFV gene mutation analysis in patient with PFAPA [PDF]

Introduction : syndrome PFAPA (periodic fever, aphthous mouth, pharyngitis and adenitis) is a clinical syndrome that usually occur in children younger than 5 years.
حسینی اصل, سید سعید, صالح زاده, فرهاد, واحدی نمین, مریم   +2 more
core   +1 more source

Two distinct fetal‐type signatures characterize juvenile myelomonocytic leukemia

HemaSphere, Volume 9, Issue 3, March 2025.
Abstract Juvenile myelomonocytic leukemia (JMML) is an aggressive clonal myeloproliferative neoplasm that affects infants and young children. The narrow window of onset suggests that age‐related factors are involved in leukemogenesis. To investigate whether ontogeny‐related features are involved in JMML oncogenesis, we compared the gene expression ...
Marion Strullu, Chloé Arfeuille, Aurélie Caye‐Eude, Loïc Maillard, Elodie Lainey, Florian Piques, Bruno Cassinat, Fabien Guimiot, Jean‐Hugues Dalle, André Baruchel, Christine Chomienne, Dominique Bonnet, Michèle Souyri, Hélène Cavé   +13 more
wiley   +1 more source