Fever tree revisited: From malaria to autoinflammatory diseases [PDF]
, 2015 Over the centuries the idea of recurrent fevers has mainly been associated with malaria, but many other fevers, such as typhoid and diphtheria were cause for concern.
Bianco, ANNA MONICA ROSARIA +4 more
core +1 more source
Immunity, Inflammation and Disease, Volume 13, Issue 3, March 2025.ABSTRACT Background Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome has been considered as a childhood syndrome. Its etiopathogeny is unknown however, currently considered as auto‐immune inflammatory disease. Recently, a few cases of adult‐onset of PFAPA syndrome have been reported.
Jiewen Deng +3 more
wiley +1 more source
Articular manifestations in Egyptian children with familial Mediterranean fever
Egyptian Rheumatology and Rehabilitation, 2020 Background Familial Mediterranean fever (FMF) is an autosomal recessive auto-inflammatory disease. Arthritis in early-onset FMF is a common finding. The aim of this study was to assess frequency of arthritis in 200 Egyptian children with FMF and also to ...
Yomna Farag +4 more
doaj +1 more source
Familial Mediterranean fever in northwest of Iran (Ardabil): The first global report from Iran [PDF]
Familial Mediterranean fever (FMF), which is the prototype of the hereditary periodic fever syndromes, is common in the countries around the Mediterranean Sea. Considering its geographical position in the northwest of Iran, with its population of Turkish
امامی, دینا +10 more
core
Frequency of the R202Q mutation of MEFV gene in Iranian patients with premature coronary artery disease: a report from West Azerbaijan province of Iran [PDF]
Health Science MonitorBackground & Aims: Premature coronary artery disease (CAD) is common in men and women under 45 and 55 years, respectively. It has been demonstrated that R202Q mutation of MEFV gene may increase the risk of cardiovascular disease in individuals with ...
Morteza Bagheri +6 more
doaj
The emerging role of neutrophil extracellular traps in autoimmune and autoinflammatory diseases
MedComm, Volume 6, Issue 3, March 2025.Neutrophil extracellular traps (NETs) released by neutrophils in response to pathogens exhibit dual anti‐inflammatory and proinflammatory effects. While effective in pathogen capture and inflammation resolution, imbalanced NET formation can lead to tissue damage and exacerbate inflammatory responses in autoimmune diseases.
Liuting Zeng +4 more
wiley +1 more source
1Novel
BMC Medical Genetics, 2010 Background Familial Mediterranean fever is a recessive autoinflammatory disease frequently encountered in Armenians, Jews, Arabs and Turks. The MEFV gene is responsible for the disease. It encodes a protein called pyrin/marenostrin involved in the innate
Jalkh Nadine +4 more
doaj +1 more source
“You can't do this, you've arthritis":Exploring the experiences of education and employment of young people with arthritis [PDF]
, 2018 Introduction: Vocational development is an integral component of adolescence with several key educational transitions occurring during this stage of life.
Farre, Albert +4 more
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Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond. [PDF]
, 2015 Cells have a number of mechanisms to maintain protein homeostasis, including proteasome-mediated degradation of ubiquitinated proteins and autophagy, a regulated process of ‘self-eating’ where the contents of entire organelles can be recycled for other ...
A Halle +162 more
core +1 more source
Increased frequency of MEFV genes in patients with epigastric pain syndrome
Balkan Journal of Medical Genetics, 2017 Atypical clinical forms of familial Mediterranean fever (FMF) can be misdiagnosed as therapy-resistant epigastric pain syndrome (EPS) for they share many of the same clinical features, such as abdominal pain. Thus, we aimed to determined the frequency of
Coskun BD +4 more
doaj +1 more source