Results 11 to 20 of about 1,294,883 (245)

Genetic analysis of MEFV mutation negative familial Mediterranean fever for non-MEFV mutations is rarely effective [PDF]

Pediatr Rheumatol Online J, 2015
Background Systemic autoinflammatory diseases (SAIDs) are a group of diseases characterized by episodes of inflammation, usually manifested with fever and a variety of symptoms, including skin-rash, arthritis and abdominal pain.
Ben-Zvi I, Shinar Y, Cohen R, Grossman C, Kukuy O, Livneh A.   +5 more
europepmc   +4 more sources

Frequencies of the MEFV Gene Mutations in Azerbaijan

Balkan Journal of Medical Genetics, 2022
The MEFV (familial Mediterranean fever gene) researches were performed in the population of the Republic of Azerbaijan in 2016–2021. Seven mutations of the MEFV gene were identified in heterozygous, homozygous and compound homozygous conditions: R761H ...
Huseynova LS, Mammadova SN, Aliyeva KAA
doaj   +3 more sources

Impact of Mediterranean Fever Gene Mutations on Clinical Characteristics in Patients With Inflammatory Bowel Disease [PDF]

Gastro Hep Advances
Background and Aims: The Mediterranean fever (MEFV) gene, which encodes a pyrin protein, is the causative gene of familial Mediterranean fever. Patients with inflammatory bowel disease (IBD) have a significantly higher frequency of MEFV mutations than ...
Tomoya Nakamura, Kohei Wagatsuma, Yuki Hayashi, Hiromu Morikubo, Daisuke Saito, Masashi Idogawa, Masanori Nojima, Jun Miyoshi, Minoru Matsuura, Tadakazu Hisamatsu, Hiroshi Nakase   +10 more
doaj   +2 more sources

MEFV Gene Mutation Analysis in Children with Immunoglobulin A Vasculitis and Its Effects on Clinical Manifestations: A Big Series from a Tertiary Center

Haseki Tıp Bülteni
Aim: Immunoglobulin A vasculitis (IgAV) is the most common vasculitis of childhood, but its pathogenesis is largely unknown, despite evidence pointing to various environmental and genetic factors. We investigated the frequency of MEFV gene mutations that
Sema Yildirim, Zeynep Karakaya, Ozlem Ozcay, Muferet Erguven   +3 more
doaj   +2 more sources

Assessment of Nutritional Status in Children with Familial Mediterranean Fever Using Prognostic Nutritional Index and Controlling Nutritional Status Score: Relationship with Clinical Findings and MEFV Mutations [PDF]

Children
Background/Objectives: The effect of nutritional status on the prognosis of Familial Mediterranean Fever (FMF), a hereditary autoinflammatory illness, is unclear.
Seyda Dogantan, Adem Keskin, Burcu Bozkaya Yücel, Peren Perk, Emel Hatun Aytaç Kaplan, Rahime Koç, Sanem Eren Akarcan   +6 more
doaj   +2 more sources

MEFV mutations in Northwest of Iran: a cross sectional study [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s):Familial Mediterranean Fever (FMF) is an autosomal recessive disorder characterized by recurrent episodes of fever accompanied by peritonitis, pleurisy, and arthritis.
Morteza Jabbarpour Bonyadi, Sousan Mir Najd Gerami, Mohammad Hossein Somi, Saeed Dastgiri   +3 more
doaj   +3 more sources

MEFV gene mutation distrubution in Azerbaijan population [PDF]

Pediatric Rheumatology, 2015
Familial Mediterranean fever (FMF)(MIM 249100) is a hereditary autoinflammatory disorder characterized by episodes of inflammation in the absence of high-titer autoantibodies or antigen-specific T cells. The Mediterranean fever (MEFV) gene(OMIM 608107) located on chromosome 16p13.3, which encodes the 781-amino-acid protein pyrin, is the causative gene ...
A Berdeli, A Oz, G Mukhtarova, S Musayev
core   +3 more sources

Immunogenic Potential of the Mediterranean Fever Gene in Patients with Coronavirus Disease: A Cross-Sectional Study [PDF]

Iranian Journal of Medical Sciences, 2023
Background: In December 2019, an outbreak of pneumonia caused by the novel coronavirus disease 2019 (COVID-19) became a pandemic and caused a global health crisis.
Farhad Salehzadeh, Farhad Pourfarzi, Rasool Molatefi, Behzad Davarnia, Ehsan Shahbazfar, Farzad Ahmadabadi   +5 more
doaj   +1 more source

Association of MEFV mutations and vascular involvement in Behcet’s disease: a study from Hatay, Turkey

Rheumatology, 2022
Introduction In this study, we aimed to determine the frequency of MEFV mutations in Behçet’s disease (BD) and to investigate the relationship between clinical findings of the disease and the MEFV mutations.
Gamze Serarslan, Sibel Elmacıoğlu Cura, Gezmiş Kimyon, Gökhan Üçgül, Mehmet Karadağ   +4 more
doaj   +1 more source

MEFV mutations in Beh�et's disease [PDF]

Human Mutation, 2000
Familial Mediterranean fever (FMF) and Behçet's disease (BD), both inflammatory diseases, are highly prevalent in the Middle Eastern and Mediterranean populations. FMF is a Mendelian autosomic recessive disease linked to MEFV, a gene of unknown function.
I, Touitou, X, Magne, N, Molinari, A, Navarro, A L, Quellec, P, Picco, M, Seri, S, Ozen, A, Bakkaloglu, A, Karaduman, J M, Garnier, J, Demaille, I, Koné-Paut   +12 more
openaire   +2 more sources