Results 21 to 30 of about 1,294,883 (245)

MEFV mutations in systemic JIA [PDF]

Pediatric Rheumatology, 2008
Results 2 carrier for M694V and two patients who were homozygote for MEFV mutations. Both of these patients were among the most severe patients in the group. One had an excellent response to etanercept whereas the other was resistant to anti-TNF and other conventional treatments and had only a partial response to thalidomide.
Aktay Ayaz N, Bilginer Y, Yilmaz E, Ergüven M, Topaloglu R, Bakkaloglu A, Ozen S   +6 more
openaire   +2 more sources

Prevalence of the MEFV gene mutations and their clinical correlations in Azeri Turkish patients with childhood Henoch-Schonlein purpura: The role of M680I and E148Q mutations [PDF]

Journal of Analytical Research in Clinical Medicine, 2015
Introduction: Patients with Henoch-Shonlein purpura (HSP) have higher rates of Mediterranean fever (MEFV) mutations comparing general population. To our knowledge, there is no report in this regard among Azeri Turkish children.
Mandana Rafeey, Morteza Jabbarpour-Bonyadi, Behzad Aliyari, Mahnaz Sadeghi-Shabestari, Fakhrossadat Mortazavi   +4 more
doaj   +1 more source

MEFV mutation frequency and effect on disease severity in ankylosing spondylitis.

TURKISH JOURNAL OF MEDICAL SCIENCES, 2014
To define the frequency of familial Mediterranean fever gene (MEFV) mutations in ankylosing spondylitis (AS) and describe different clinical aspects of MEFV mutation carrier and noncarrier AS patients.In 112 AS patients, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) scores were ...
Y. Maraş, A. Akdoğan, B. Kısacık, L. Kılıç, E. Yılmaz, A. Tufan, U. Kalyoncu, S. Apraş Bilgen, S. Kiraz, A. Ertenli, M. Çalgüneri   +10 more
semanticscholar   +4 more sources

Repeated Necrotizing Lymphadenitis with MEFV Gene Mutations.

Internal medicine (Tokyo, Japan), 2021
We herein report a 36-year-old man with repeated necrotizing lymphadenitis due to MEFV gene mutations. The patient's chief complaints were a fever and painful cervical lymphadenopathy. We diagnosed him with necrotizing lymphadenitis based on the pathological findings of the lymph nodes and the exclusion of other differential diseases.
Yamamura, Yuta, Furuichi, Kengo, Toyama, Tadashi, Oshima, Megumi, Ogura, Hisayuki, Sato, Koichi, Nakagawa, Shiori, Miyagawa, Taro, Kitajima, Shinji, Hara, Akinori, Iwata, Yasunori, Sakai, Norihiko, Shimizu, Miho, Ikeda, Hiroko, Toma, Tomoko, Takasawa, Kazuya, Yachie, Akihiro, Wada, Takashi   +17 more
openaire   +2 more sources

The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis

Pediatric Rheumatology Online Journal, 2020
Background Systemic juvenile idiopathic arthritis (sJIA) has many clinical features overlapping with familial Mediterranean fever (FMF), which is caused by mutations in MEFV gene. And FMF patients were easily misdiagnosed as sJIA in China.
Linqing Zhong, Wei Wang, Ji Li, Mingsheng Ma, Lijuan Gou, Changyan Wang, Zhongxun Yu, Tiannan Zhang, Yanqing Dong, Qijiao Wei, Hongmei Song   +10 more
doaj   +1 more source

Unusual presentation of familial Mediterranean fever with co‐existing polyarteritis nodosa and acute post‐streptococcal glomerulonephritis

Clinical Case Reports, 2022
Acute post‐streptococcal glomerulonephritis (APSGN) and polyarteritis nodosa (PAN) may occur simultaneously after streptococcal infection in a child who is previously healthy but carries a Mediterranean fever (MEFV) mutation.
Yeşim Özdemir Atikel, Betül Emine Derinkuyu, Sevcan A. Bakkaloğlu   +2 more
doaj   +1 more source

Genetic and Epigenetic Regulation of MEFV Gene and Their Impact on Clinical Outcome in Auto-Inflammatory Familial Mediterranean Fever Patients

Current Issues in Molecular Biology, 2023
Epigenetic modifications play a pivotal role in autoimmune/inflammatory disorders and could establish a bridge between personalized medicine and disease epidemiological contexts.
May E. Zekry, Al-Aliaa M. Sallam, Sherihan G. AbdelHamid, Waheba A. Zarouk, Hala T. El-Bassyouni, Hala O. El-Mesallamy   +5 more
doaj   +1 more source

MEFV mutations in systemic onset juvenile idiopathic arthritis [PDF]

Rheumatology, 2008
Autoinflammatory diseases constitute a large spectrum of monogenic diseases like FMF or cryopyrin-associated periodic syndromes (CAPS) and complex genetic trait diseases such as systemic onset juvenile idiopathic arthritis (SoJIA). An increased rate of MEFV mutations has been shown among patients with PAN and HSP, in populations where FMF is frequent ...
N A, Ayaz, S, Ozen, Y, Bilginer, M, Ergüven, E, Taşkiran, E, Yilmaz, N, Beşbaş, R, Topaloğlu, A, Bakkaloğlu   +8 more
openaire   +2 more sources

Mediterranean fever gene mutations in patients with idiopathic mesangial proliferative glomerulonephritis [PDF]

Journal of Nephropathology, 2018
Background: Familial Mediterranean Fever (FMF) is the most common inherited autoinflammatory disease. Kidney involvement in FMF is usually attributed to secondary amyloidosis. Non-amyloid glomerular involvement has also been reported.
Jalal Etemadi, Taraneh Majidi, Roza Motavalli, Mortaza Bonyadi, Sepideh Zununi Vahed, Behzad Zaker, Mohammadreza Ardalan   +6 more
doaj   +1 more source

Patient with FMF and Triple MEFV Gene Mutations [PDF]

Medical Archives, 2015
Familial Mediterranean fever (FMF) is the most common auto-inflammatory disease with monogenic (MEditerranean FeVer -MEFV- gene) inherited pattern. It mainly affects ethnic groups living along the eastern Mediterranean Sea: Turks, Sephardic Jews, Armenians, and Arabs [1]. Today FMF is not rare disease in other Mediterranean ethnicities, such as Greeks,
Salehzadeh, Farhad, Fathi, Afshin
openaire   +2 more sources