A case with cytomegalovirus colitis and toxic megacolon initially diagnosed as Crohn's disease
Shan-Han Chang +3 more
doaj +2 more sources
A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]
Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian +12 more
core +2 more sources
Outcome of Toxic Megacolon during Pregnancy
Two patients with ulcerative colitis required subtotal colectomy and ileostomy for toxic megacolon during pregnancy. Subsequently, a mucosal proctectomy with ileal pouch-anal anastomosis was performed. These two patients who avoided permanent ileostomies
Carl Chartrand-Lefebvre +4 more
doaj +1 more source
Toxic megacolon is a severe complication of Clostridium difficile infection (CDI) with a high percentage of mortality. The mainstay of treatment is currently represented by medical management, while surgical intervention is indicated in patients not ...
Addolorata Masiello +5 more
doaj +1 more source
Risk factors for recurrence in patients with Clostridium difficile infection due to 027 and non-027 ribotypes [PDF]
Objectives: Our objective was to evaluate factors associated with recurrence in patients with 027+ and 027– Clostridium difficile infection (CDI). Methods: Patients with CDI observed between January and December 2014 in six hospitals were consecutively ...
Aceti, A. +19 more
core +1 more source
Severe Clostridium difficile infections in intensive care units: Diverse clinical presentations
Background: Clostridium difficile infections (CDIs) cause significant mortality and morbidity. Critically ill patients are susceptible to CDIs and tend to have severe CDIs, and their clinical presentations are not merely diarrhea.
Jen-Chieh Lee +4 more
doaj +1 more source
Imaging of ischemia, obstruction and infection in the abdomen [PDF]
Intestinal ischemia is a serious condition that continues to be associated with mortalities in excess of 70%. Intestinal obstruction and gastrointestinal tract sepsis are common conditions, accounting for a large proportion of patients admitted to ...
Maher, Michael M. +4 more
core +1 more source
Profile of Trypanosoma cruzi Infection in a Tropical Medicine Reference Center, Northern Italy [PDF]
Chagas disease (CD) is endemic in Central and South America, Mexico and even in some areas of the United States. However, cases have been increasingly recorded also in non-endemic countries.
Angheben, A +10 more
core +3 more sources
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Risk for Clostridium difficile infection after allogeneic hematopoietic cell transplant remains elevated in the postengraftment period [PDF]
BACKGROUND: Clostridium difficile infection (CDI) is a frequent cause of diarrhea among allogeneic hematopoietic cell transplant (HCT) recipients. It is unknown whether risk factors for CDI vary by time posttransplant.
Bommarito, Kerry M +8 more
core +2 more sources

