Integrating "Yang transforming Qi and Yin constituting the body" with immune regulation: an evidence synthesis of multidimensional traditional chinese medicine therapy for immune thrombocytopenia. [PDF]
Zhou X, Jiang Y, Hou M, Shan N.
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Electroacupuncture as a tool to stimulate bone marrow megakaryocytes in mice: A pilot study. [PDF]
Dos Santos Mariani LPR +4 more
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Inflammatory mediators differentially regulate megakaryopoiesis and thrombopoiesis in myelofibrosis and essential thrombocythemia. [PDF]
Yañuk DB +12 more
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Anti-CD19 chimeric antigen receptor T cells in Evans syndrome of systemic lupus erythematosus. [PDF]
Lang M +6 more
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Heterozygous nonsense <i>FLI1</i> p.Met100∗ variant results in thrombocytopenia and increased erythroid gene expression. [PDF]
Zhang H +14 more
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Endomitosis: a new cell fate in the cell cycle leading to polyploidy in megakaryocytes and hepatocytes. [PDF]
Hua QH, Zhang X, Tian R, She Z, Huang Z.
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Megakaryocytes are commonly known as large, polyploid, bone marrow resident cells that contribute to hemostasis through the production of platelets. Soon after their discovery in the 19th century, megakaryocytes were described in tissue locations other than the bone marrow, specifically in the lungs and the blood circulation.
Florian Puhm +2 more
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Megakaryocyte and polyploidization
Experimental Hematology, 2018In mammals, platelets are produced in the blood by cytoplasmic fragmentation of megakaryocytes (MKs). Platelet production is thus dependent on both the MK number and size. During differentiation, MKs switch from a division by mitosis to polyploidization by endomitosis to increase their size. The endomitotic process includes several successive rounds of
Stefania, Mazzi +4 more
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Megakaryocytes in pulmonary diseases
Life Sciences, 2022Megakaryocytes (MKs) are typical cellular components in the circulating blood flowing from the heart into the lungs. Physiologically, MKs function as an important regulator of platelet production and immunoregulation. However, dysfunction in MKs is considered a trigger in various diseases.
Di-Yun, Huang +6 more
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