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Megakaryocytes and Megakaryocyte Progenitors in Human Cord Blood

Journal of Pediatric Hematology/Oncology, 1992
Thrombocytopenia contributes significantly to morbidity in the sick term or preterm infant. However, few data exist on newborn's megakaryocytes and megakaryocyte progenitor cells (CFU-MK). We therefore studied CFU-MK in term and preterm infant cord blood and compared the results with data on CFU-MK from adult bone marrow and adult peripheral blood in a
T A, Olson   +4 more
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Immature megakaryocytes in the mouse: In vitro relationship to megakaryocyte progenitor cells and mature megakaryocytes

Journal of Cellular Physiology, 1982
AbstractAn assay describing conditions for the maturation of single immature megakaryocytes in vitro is reported. Enriched populations of small, relatively immature megakaryocytes have been found to develop into single, mature megakaryocytes by 60 hours in semisolid agar cultures.
Long, M W, Williams, N, Mcdonald, T P
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Circulating megakaryocytes

Histopathology, 1982
Cells resembling the smaller variants of the Warthin‐Finkeldey giant cells of measles were observed in the pulmonary alveolar capillaries in a high percentage of primates and humans apparently free from pathological changes associated with measles. Cells resembling megakaryocytes were found also in the liver and spleen in both groups but only in a ...
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Megakaryocytes muscle in

Blood, 2010
In this issue of Blood, Halene and colleagues reveal an essential function of the transcription factor SRF during megakaryocyte maturation and platelet formation. The spectrum of SRF-regulated genes overlaps with SRF targets in muscle cells, including those involved in actin cytoskeletal dynamics.
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Megakaryocytic Myelosis in a Cat

Journal of the American Veterinary Medical Association, 1976
SUMMARY A myeloproliferative disorder in a cat was characterized by abnormal proliferation of megakaryocytes in the bone marrow and by severe, nonregenerative anemia. The number of circulating thrombocytes was increased markedly, with many giant and morphologically bizarre forms.
R L, Michel, P, O'Handley, A W, Dade
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The origin of the megakaryocyte

Nature Cardiovascular Research, 2022
Kellie R. Machlus, Eric Boilard
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Megakaryocytic Leukemia in a Dog

Veterinary Pathology, 1978
Most leukemias of dogs involve neutrophilic precursors. Monocytic leukemia is less common and only single cases of basophilic, megakaryocytic and erythroid leukemia in the canine species have been recorded [7]. A case of megakaryocytic leukosis of questionable neoplastic nature in a dog also has been described [lo].
M A, Holscher   +3 more
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Megakaryocytes in Renal Glomeruli

American Journal of Clinical Pathology, 1981
Reported are 27 autopsies with significant increases in the numbers of megakaryocytes within the renal glomerular capillary network (P less than 0.001). These were selected from 118 cases in which peripheral vascular megakaryocytosis could be expected preterminally.
W L, Broghamer, B, Weakley-Jones
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ACUTE MEGAKARYOCYTIC LEUKEMIA

Archives of Internal Medicine, 1948
THERE have been many observations in medical literature in which megakaryocytes have been described as a prominent feature in pathologic conditions of the blood. The number of these cells is frequently increased in thrombocytothemia and polycythemia vera.
J B, McDONALD, J G, HAMRICK
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Immunological face of megakaryocytes

Frontiers of Medicine
Megakaryocytes (MKs), which are traditionally known for their role in platelet production, are now emerging as unique immune cells with diverse capabilities. They express immune receptors, participate in pathogen recognition and response, phagocytose pathogens, contribute to antigen presentation, and interact with various immune cell types.
Yueying, Li   +2 more
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