Results 171 to 180 of about 34,194 (287)

Acquired Amegakaryocytic Thrombocytopenia Presenting as Pancytopenia in a Patient With Chronic Lymphocytic Leukemia: A Case Report. [PDF]

Case Rep Hematol
Chen CC, Shah A, Andrawis M, Benjamin J, Shah M, Fratella-Calabrese A, Chang VT.   +6 more
europepmc   +1 more source

Immune and cellular determinants of response to HMA‐venetoclax regimens in acute myeloid leukemia

HemaSphere, Volume 10, Issue 10, October 2026.
Abstract Hypomethylating agents (HMAs) combined with Venetoclax have reshaped the therapeutic landscape of acute myeloid leukemia (AML), yet the biological determinants of response remain unclear. We integrated clinical and genomic profiling in 132 newly diagnosed or relapsed/refractory AML patients treated with HMA‐Venetoclax and performed single‐cell
Alfredo Marchetti, Francesca Lazzaroni, Matteo Claudio Da Via', Marta Lionetti, Giulia Maggioni, Alessia Campagna, Denise Ventura, Giorgio A. Croci, Alessio Marella, Akihiro Maeda, Antonio Matera, Emanuele Calvi, Margherita Scopetti, Filippo Viviani, Nicolò Rampi, Davide Bonometti, Elena Benzoni, Manuela Zappa, Sonia Fabris, Marzia Barbieri, Stefania Pioggia, Claudia Leoni, Antony Ricchiuti, Matteo G. D. Porta, Mariarita Sciumè, Francesco Passamonti, Nicola S. Fracchiolla, Niccolò Bolli   +27 more
wiley   +1 more source

Megakaryocytes Internalize and Are Activated by Immune Complexes. [PDF]

Circ Res
Puhm F, Allaeys I, Petito E, Sang Y, Tupin F, Dos Santos Pereira Andrade A, Doré E, Dubuc I, Vaillancourt M, Dieudé M, Hébert MJ, Florea BI, Trépanier P, Washington VA, Senis Y, Fortin PR, Brisson AR, Wolberg AS, Bury L, Flamand L, Boilard E.   +20 more
europepmc   +1 more source

Identification of SORT1 as a Key Regulator of Antigen Presentation in CD16+ Monocytes During Septic Shock via Multi‐Omics and In Silico Gene Knockout Analysis

Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Objective This study aimed to screen and identify hub genes correlated with septic shock through integrative analyses of bulk transcriptomics, machine learning, weighted gene co‐expression network analysis (WGCNA), single‐cell transcriptomics, and in silico gene knockout, and further dissect their underlying immunoregulatory mechanisms ...
Shulu Wu, Jiaying Zhang, Shiqi Guo, Yuting Hu, Hui Shen, Yingjie Xu, Bining Yang   +6 more
wiley   +1 more source

Dual-Driver Myeloproliferative Neoplasm: Concurrent p190 <i>BCR::ABL1</i> CML and <i>JAK2</i> V617F Mutation: A Case Report and Literature Review. [PDF]

Case Rep Hematol
Elkady M, Jin Y, Zhao W.
europepmc   +1 more source

Plerixafor and G‐CSF Versus Placebo and G‐CSF in Moderately Mobilizing Patients With Multiple Myeloma to Optimize Hematopoietic Stem Cell Collection Results (OPTIMIZE)

Journal of Clinical Apheresis, Volume 41, Issue 5, October 2026.
ABSTRACT Efficient collection of hematopoietic progenitor cells (HPCs) is essential for autologous stem cell transplantation (ASCT) in multiple myeloma (MM). Although plerixafor is routinely used in poor mobilizers, its role in patients with intermediate mobilization capacity remains unclear.
Worel Nina, Schreder Martin, Tanzmann Andreas, Kurz Martin, Huber‐Kraßnitzer Bianca, Neumeister Peter, Rosskopf Konrad, Sareban Nazanin, Branka Manuela, Kolovratova Vera, Oesterreicher Sophia, Koerbler Beatrix, Kitzweger Elvira, Ruckser Reinhard, Rabitsch Werner, Agis Hermine, Krauth Maria, Greinix Hildegard T.   +17 more
wiley   +1 more source

ON THE ALLEGED PHAGOCYTOSIS BY MEGAKARYOCYTES [PDF]

British Journal of Haematology, 1981
openaire   +2 more sources

Extramedullary hematopoiesis presenting as a large adrenal mass mimicking adrenocortical carcinoma in a primary myelofibrosis patient: A case report. [PDF]

Urol Case Rep
Rakhshan A, Besharati S, Moradi Shahrbaback M, Yousefi M.   +3 more
europepmc   +1 more source

Connection between metastatic breast cancer and megakaryocytes in bone marrow

Breast cancer is the second leading cause of cancer death in women. Approximately 13% of women will develop breast cancer in their lifetime and rates continue to rise.
Studer, Tristin Nathanial
core  

Reversible Eltrombopag‐Associated Bone Marrow Fibrosis With Hematologic Recovery After Drug Withdrawal in ASXL1‐Mutated Hypoplastic Myelodysplastic Syndrome: A Case Report

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Hypoplastic myelodysplastic syndrome (MDS) often overlaps clinically with aplastic anemia and frequently involves clonal hematopoiesis. Thrombopoietin receptor agonists (TPO‐RAs), including eltrombopag, are increasingly used to treat cytopenias in hypoplastic marrow failure syndromes; however, their long‐term effects on clonal dynamics and ...
Kyoko Yoshihara, Ikuo Matsuda, Yasuhito Nannya, Mami Samori, Naru Tomigaki, Saki Takahashi, Chisato Ohe, Satoshi Yoshihara   +7 more
wiley   +1 more source