Results 161 to 170 of about 34,194 (287)

Proteomics of heterogeneous megakaryocytes identifies JI051 as an enhancer of platelet biogenesis. [PDF]

open access: yesLife Sci Alliance
Taga R   +9 more
europepmc   +1 more source

Myelodysplastic Syndromes‐Transformed Acute Myeloid Leukemia With Concurrent DEK::CAN Fusion Gene Positivity and WT1 Overexpression: A Case Report and Literature Review

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic stem cell disorders with a risk of progression to acute myeloid leukemia (AML). MDS‐transformed AML (MDS‐AML) has a poor prognosis. The concurrent presence of DEK::CAN fusion gene positivity and WT1 overexpression is extremely rare and likely denotes a highly ...
Wanxiu Mao   +5 more
wiley   +1 more source

Collagen or collagen-related peptide cause (Ca2+)i elevation and increased tyrosine phosphorylation in human megakaryocytes.

open access: yes, 1999
Since megakaryocytes are the cellular precursors of platelets we have investigated whether they share responses to platelet agonists, in particular collagen.
Melford, S K   +4 more
core   +1 more source

Insights Into the Role of Platelet Factor 4 in Neurodegenerative Diseases

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This review summarizes potential functions of platelet factor 4 (PF4) in neurodegenerative diseases (NDs) and discusses its promise as both a biomarker and a therapeutic target. Further elucidation of PF4 signaling pathways may provide new insights into disease mechanisms and uncover novel opportunities for targeted interventions in NDs.
Qi Tian   +3 more
wiley   +1 more source

Visceral Leishmaniasis in an Immunocompromised Patient: Diagnostic Bone Marrow Cytomorphology [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Manjari Kishore, Garima Baweja Madaan
doaj   +1 more source

MAFG as a Redox‐Sensitive Node Linking Peripheral Immune Reprogramming to Cognitive Risk in the Sepsis‐to‐Alzheimer's Disease Continuum: Single‐Cell Dissection and Adoptive‐Transfer Validation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Sepsis reprograms circulating immune cells, raising the redox‐sensitive transcription factor MAFG in myeloid progenitors, dendritic cells, and platelets and suppressing their amyloid‐β scavenger receptors. Silencing MAFG restores amyloid‐β clearance, reduces cerebral plaques and microglial activation, and preserves cognition in APP/PS1 mice.
Xiaoyu Xiang   +7 more
wiley   +1 more source

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