Results 141 to 150 of about 34,194 (287)

Development of a Machine Learning Algorithm for Differential Diagnosis Between Primary Immune Thrombocytopenia and Connective Tissue Disease-Related Thrombocytopenia in Pediatric Patients. [PDF]

J Clin Lab Anal
Primary immune thrombocytopenia (ITP) and connective tissue disease‐related thrombocytopenia (CTD‐TP) share overlapping initial presentations in children, often leading to delayed diagnosis and suboptimal management. While existing literature focuses on therapeutic strategies, this study is the first to develop a machine learning (ML)‐based diagnostic ...
Kang F, Yan M, Yue Y, Wang X, Liu Y.
europepmc   +2 more sources

Analysis of megakaryocytes by flow cytometry.

, 1998
A flow cytofluorometric measurement of megakaryocyte ploidy has been adapted from Tomer's method. Briefly, bone marrow is aspirated through a medium containing theophyllin, prostaglandin-E1 and other antiaggregant agents.
Chatelain, Christian, Symann, Michel, Baatout, S., Staquet, P.   +3 more
core  

Acquired Elliptocytosis With Hemolytic Anemia in Myelodysplastic Neoplasm With del(20q)

International Journal of Laboratory Hematology, EarlyView.
Nina Sicard, Léa Ousset, Karen Delavigne, Isabelle Luquet, Jean‐Baptiste Rieu   +4 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, Volume 46, Issue 11, Page 3973-3988, November 2026.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Inflammatory Pseudotumour in Common Seal (Phoca vitulina): A Case Report

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A 19‐year‐old intact male common seal (Phoca vitulina) diagnosed with a chronic ulcer. Microbiology identified Vibrio alginolyticus. Radiography noted phalanx alterations. Macroscopic, histopathological, and immunohistochemical examinations revealed a neoplastic origin with a myofibroblastic phenotype. This report describes the first documented case of
Javier M. De Pablo‐Moreno, Rocío Canales, Mireia Mainez, Nicolás Aradilla, Blanca Chinchilla, Néstor Porras, Ignacio Vargas‐Castro, Antonio Rodríguez‐Bertos   +7 more
wiley   +1 more source

Giant Elliptical Platelets as a Cytological Component in MYH9‐Related Disease

International Journal of Laboratory Hematology, EarlyView.
Márcio Antonio W. Melo, Cristina M. Silveira, Maíra M. Ribeiro, Evilly R. O. Magalhães, Gabriela S. Arcanjo   +4 more
wiley   +1 more source

Precursor‐targeted immune‐mediated anaemia in a dog with concurrent haemoparasite seroreactivity: Diagnostic challenges and therapeutic response

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary Precursor‐targeted immune‐mediated anaemia (PIMA) is an increasingly recognised cause of nonregenerative anaemia in dogs and may be difficult to distinguish from infectious or other immune‐mediated conditions. This report describes a dog presenting severe nonregenerative anaemia, leukopenia and thrombocytopenia, initially testing seroreactive ...
Vinícius dos Santos Resende Rodrigues, Ellen Cristina Araújo de Medeiros, João Alfredo Biagi Camargo Neto, Igor Luiz Salardani Senhorello, Suely Regina Mogami Bomfim, Nayro Xavier de Alencar   +5 more
wiley   +1 more source

Necrotic adrenal myelolipoma in a geriatric dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Adrenal myelolipomas are rare in dogs and usually incidental findings. They appear as hyperechoic, heterogeneous masses on ultrasound and fat‑dominant lesions on computed tomography (CT). An 11‑year‑old Spaniel cross presented with a 2‑day history of diarrhoea, vomiting and polyuria/polydipsia.
Heather Durkin, Sophie Aspinall
wiley   +1 more source

First Report of MPL c.23T>G (p.M8R) Variant in Congenital Amegakaryocytic Thrombocytopenia: A Case Report

eJHaem
Congenital amegakaryocytic thrombocytopenia is a rare inherited bone marrow failure syndrome primarily caused by MPL gene mutations. It presents with severe neonatal thrombocytopenia and typically progresses to pancytopenia.
Atbin Latifi, Sina Yousefian
doaj   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source