Results 131 to 140 of about 27,974 (255)

MPL receptor dimerization and the thrombopoietin pathway in primary immune thrombocytopenia: from molecular mechanisms to targeted therapies. [PDF]

Front Med (Lausanne)
Wang Y, Liu C, Hu Y, Sun X, Zhang W, Zhu W.   +5 more
europepmc   +1 more source

Molecular and Functional Platelet Abnormalities in Myeloproliferative Neoplasms. [PDF]

Cells
Wang AX, Guo BB, Linden MD.
europepmc   +1 more source

The LAV‐BPIFB4‐Platelet‐CD47 Axis: A Novel Mechanism Associated With Immune Resilience in Longevity

Aging Cell, Volume 25, Issue 7, July 2026.
Centenarians display elevated CD47+ reticulated platelets, a trait recapitulated in LAV‐BPIFB4 carriers on total platelet pool. LAV‐BPIFB4 drives an early acquirement of CD47 surface expression, enabling platelets to suppress monocyte IL‐6 release. rhLAV‐BPIFB4 phenocopies the effects in non‐genetic carriers, establishing the platelet–CD47–monocyte ...
Elena Ciaglia, Roberta Maria Esposito, Valentina Lopardo, Francesco Montella, Cristina Basile, Roberta Longo, Anna Maciag, Giuseppe Rescigno, Antonio Damato, Francesco Del Plato, Alfonso Finizio, Carmine Vecchione, Albino Carrizzo, Annibale Alessandro Puca   +13 more
wiley   +1 more source

The role of <i>MXRA7</i> in bone marrow senescence involves macrophage polarization and microenvironment remodeling. [PDF]

Blood Sci
Qin Y, Zhao Z, Chen Y, Zheng Y, Ma K, Lin D, Liu X, Wang Y.   +7 more
europepmc   +1 more source

Real‐World Safety and Efficacy of Avatrombopag in Adults with Immune Thrombocytopenia: A Systematic Review and Meta‐Analysis

European Journal of Haematology, Volume 117, Issue 1, Page 174-185, July 2026.
ABSTRACT Objective This systematic review and meta‐analysis aimed to evaluate the risk of thromboembolic events and assess the overall safety and effectiveness of avatrombopag in adult patients with immune thrombocytopenia using real‐world evidence. Methods A systematic search was conducted following the PRISMA 2020 guidelines.
M. L. Lozano, D. Valcarcel
wiley   +1 more source

Circadian clock regulation of hemostasis: a systematic review of molecular pathways. [PDF]

Res Pract Thromb Haemost
Ibrahim Z, Murphy RP, Guillaume GC, Arya R, Goswami N.   +4 more
europepmc   +1 more source

Beyond Hemostasis: Platelet Biomarkers and Vascular‐Immune Crosstalk in Dengue

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Several biomarkers are associated with platelet activation during dengue virus (DENV) infection. These include serum markers (AST, ALT, ferritin), platelet surface or secreted molecules (P‐selectin, PF4, RANTES, VEGF‐A, CD40L, TREM‐1, TLT‐1), immune and endothelial markers (TREM‐1, Ang‐1, Ang‐2), and viral components such as DENV EIII.
Amanda Beatriz Adriano da Silva‐Alencar, Amanda de Oliveira Matos, Daniel Francisco de Sousa, Jefferson do Carmo Dietz, Eugenio Damaceno Hottz, Marcelle Figueira Marques da Silva‐Sales, Helioswilton Sales‐Campos   +6 more
wiley   +1 more source

Dysregulation of the immune microenvironment in essential thrombocythemia: the interplay of core genes and inflammation-related signaling pathways. [PDF]

Front Immunol
Li Y, Chen X, Guo Y, Sha R, Hao H, Zhang J, Song H, Wei Y, Ye X.   +8 more
europepmc   +1 more source

Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy

Aggregate, Volume 7, Issue 6, June 2026.
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao, Dong Wang, Lei Wang, Hongkai Zhang, Yue Sun, Dan Ding   +5 more
wiley   +1 more source

A Review of the Pathological and Molecular Diagnosis of Primary Myelofibrosis. [PDF]

Cancers (Basel)
Shao R, Ryder C, Wang L, Zhang H, Moscinski L, Martin M, Shebes M, Li JY, Song J.   +8 more
europepmc   +1 more source