Results 131 to 140 of about 34,194 (287)
Xin yixueFerroptosis is an iron-dependently regulated form of programmed cell death driven by ironions and characterized by abnormal accumulation of lipid peroxidation products and failure of anti-oxidantdefense systems.
Weitao ZHUANG, Yuming ZHANG
doaj +1 more source
Altered inside-out and outside-in integrin signaling in Rasa3−/− megakaryocytes.
, 2014 Fetal liver cell (FLC) were isolated from E12.5 Rasa3+/+ and Rasa3−/− embryos and cultured with TPO for 3 days. Megakaryocytes were enriched on a BSA-gradient, deprived of serum for 4 hours and used in inside-out and outside-in integrin signaling assays.
Patricia Molina-Ortiz (167505) +7 more
core +1 more source
Persistent Immune Thrombocytopenia as a Post‐Acute Sequelae of COVID‐19: A Case Report
Public Health Challenges, Volume 5, Issue 4, December 2026.ABSTRACT Immune thrombocytopenia (ITP) is a recognized hematologic complication associated with coronavirus disease 2019 (COVID‐19), but its persistence years after acute infection remains uncommon. We present a case of a 52‐year‐old male who was diagnosed with COVID‐19 in June 2020. Following recovery from the acute illness, he had persistent fatigue,
Riazullah +5 more
wiley +1 more source
Immune and Inflammatory Properties of Megakaryocytes
CellsMegakaryocytes (MKs), which primarily develop in bone marrow (BM) from hematopoietic stem cells, are critical for platelet production. Beyond their well-established role in thrombopoiesis, MKs have been identified as important for BM niche maintenance ...
Shiv Vardan Singh +2 more
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Anti-Apoptotic Pathways in Bone Marrow and Megakaryocytes in Myeloproliferative Neoplasia
, 2014 Objective: Proliferative activity contributes to bone marrow cellularity in myeloproliferative neoplasia (MPN). Megakaryocytes are the most important cells in MPN bone marrow pathology.
Schouten, Harry C. +2 more
core +1 more source
Quantitative Biology, Volume 14, Issue 4, December 2026.Abstract Single‐cell RNA sequencing (scRNA‐seq) generates high‐dimensional transcriptomic data but is severely affected by dropout events, which obscure true gene–gene relationships. These missing values introduce bias into downstream analyses, complicate data processing, and reduce analytical efficiency.
Shuang Xu +3 more
wiley +1 more source
The Size of Megakaryocytes in Human Fetal, Infantile and Adult Hematopoiesis [PDF]
, 1983 It has been reported that the appearance of small megakaryocytes can be detected in various blood diseases and in fetal hematopoiesis. In the studies reported herein, we have investigated the age changes in the area of megakaryocytes during fetal stage ...
Enzan, Hideaki +3 more
core
International Journal of Laboratory Hematology, EarlyView.
Fatma AlBulushi, Eric McGinnis
wiley +1 more source
American Journal of Hematology, Volume 101, Issue 11, Page 2836-2852, November 2026.ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas +4 more
wiley +1 more source
Investigation of megakaryocytes from normal and myeloproliferative bone marrow biopsies
, 2000 Megakaryocytes are large, distinctive cells found mainly in the bone marrow. They produce platelets in accordance with changes in peripheral demand. Regulatory mechanisms for the modulated production of platelets are ill-defined.
Cheung, Manyee
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