Results 121 to 130 of about 34,194 (287)

ICSH Guidance on Bone Marrow Examination and Reporting

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber, Alexandar Tzankov, Olga Pozdnyakova, Hiromichi Matsushita, Gina Zini, Leonie Saft, on behalf of the International Council for Standardization in Haematology   +6 more
wiley   +1 more source

Size and DNA distribution of megakaryocytes in situ and differentiated in vitro.

, 2013
Megakaryocytes from a decalcified femur (A) and from a bone marrow culture (B). Because the number of megakaryocytes was similar in control and Podxl- null mice, for the sake of clarity, only images from the controls are represented. Size distribution of
Roberto Parrilla (20060), Darío Fernández (342454), Inés Sánchez (342455), Sonia Alonso-Martín (342453), Susana Larrucea (20054), Miguel Pericacho (102938), Consuelo González-Manchón (20059), Matilde S. Ayuso (322317)   +7 more
core   +1 more source

Comparison of cell line gene expression to megakaryocytes.

, 2019
Comparison of cell line gene expression to megakaryocytes.
Leonard C. Edelstein (599205), Namrata Madan (7041629), Chad A. Shaw (94130), Andrew R. Ghazi (7041632), Xianguo Kong (599201), Edward S. Chen (136174)   +5 more
core   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Platelets and megakaryocytes in cancer

Journal of Thrombosis and Haemostasis
Platelets have important roles in hemostasis but also actively participate in cancer metastasis and inflammatory processes. They are produced by large precursor cells, the megakaryocytes, residing mainly in the bone marrow. Clinically, elevated platelet counts and/or increased platelet-to-lymphocyte ratio are being explored as biomarkers of metastatic ...
openaire   +2 more sources

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

Periodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker, Sandra H. Stuhr, Gustavo Avila‐Ortiz, Andrea Pilloni, Lorenzo Marini, Rogerio Castilho, Beth I. Wallace, Yvonne L. Hernandez‐Kapila   +7 more
wiley   +1 more source

Case Report: T‐Lymphoblastic Leukemia in a Dog With Erythrophagia

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 2‐year‐old male German Shepherd dog was presented with progressive weight loss, lethargy, and hyporexia. Hematologic analysis revealed a moderate macrocytic normochromic anemia and moderate thrombocytopenia. Additionally, a pronounced leukocytosis was observed, characterized by 33% large lymphoid cells, marked neutrophilia with a significant
Francisca B. Lang, Matheus Y. dos Santos, Vinicius N. Hirata, Felipe A. B. de Sousa, Augusto de Oliveira, Lucas T. de Castro, Rafael A. Fighera, Alexandre Krause   +7 more
wiley   +1 more source

Genetic deletion of P-selectin prevents fibrosis development by inhibiting the neutrophil megakaryocyte emperipolesis in the Gata1low mouse model for myelofibrosis

European Journal of Histochemistry
Myelofibrosis (MF) is a rare chronic hematological disorder, within the family of myeloproliferative neoplasms. The MF patients present clinical abnormalities such as anemia, and thrombosis, as well as alterations in the bone marrow (BM ...
Francesca Arciprete, Viola Velardi, Antonio Di Virgilio, Paola Verachi, Claudio Carta, Giulia Pozzi, Vincenzo Roberti, Giorgio Vivacqua, Rosalba Rana, Maria Zingariello   +9 more
doaj   +1 more source

Electron microscopy of megakaryocytes in thin-layer agar cultures of mouse bone marrow

, 1974
Individual hematopoietic cells in thin-layer agar cultures of mouse bone marrow were studied with the electron microscope. The fine structure of cells which morphologically resemble megakaryocytes and which we refer to as “candidate” megakaryocytes is ...
Noord, M.J. van, Nakeff, A., Blansjaar, N.   +2 more
core  

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source