Results 241 to 250 of about 34,194 (287)
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Journal of Cellular Physiology, 1982
AbstractAn assay describing conditions for the maturation of single immature megakaryocytes in vitro is reported. Enriched populations of small, relatively immature megakaryocytes have been found to develop into single, mature megakaryocytes by 60 hours in semisolid agar cultures.
Long, M W, Williams, N, Mcdonald, T P
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AbstractAn assay describing conditions for the maturation of single immature megakaryocytes in vitro is reported. Enriched populations of small, relatively immature megakaryocytes have been found to develop into single, mature megakaryocytes by 60 hours in semisolid agar cultures.
Long, M W, Williams, N, Mcdonald, T P
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Megakaryocytes in pulmonary diseases
Life Sciences, 2022Megakaryocytes (MKs) are typical cellular components in the circulating blood flowing from the heart into the lungs. Physiologically, MKs function as an important regulator of platelet production and immunoregulation. However, dysfunction in MKs is considered a trigger in various diseases.
Di-Yun, Huang +6 more
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Blood, 2010
In this issue of Blood, Halene and colleagues reveal an essential function of the transcription factor SRF during megakaryocyte maturation and platelet formation. The spectrum of SRF-regulated genes overlaps with SRF targets in muscle cells, including those involved in actin cytoskeletal dynamics.
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In this issue of Blood, Halene and colleagues reveal an essential function of the transcription factor SRF during megakaryocyte maturation and platelet formation. The spectrum of SRF-regulated genes overlaps with SRF targets in muscle cells, including those involved in actin cytoskeletal dynamics.
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Histopathology, 1982
Cells resembling the smaller variants of the WarthinâFinkeldey giant cells of measles were observed in the pulmonary alveolar capillaries in a high percentage of primates and humans apparently free from pathological changes associated with measles. Cells resembling megakaryocytes were found also in the liver and spleen in both groups but only in a ...
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Cells resembling the smaller variants of the WarthinâFinkeldey giant cells of measles were observed in the pulmonary alveolar capillaries in a high percentage of primates and humans apparently free from pathological changes associated with measles. Cells resembling megakaryocytes were found also in the liver and spleen in both groups but only in a ...
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Megakaryocytic Myelosis in a Cat
Journal of the American Veterinary Medical Association, 1976SUMMARY A myeloproliferative disorder in a cat was characterized by abnormal proliferation of megakaryocytes in the bone marrow and by severe, nonregenerative anemia. The number of circulating thrombocytes was increased markedly, with many giant and morphologically bizarre forms.
R L, Michel, P, O'Handley, A W, Dade
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Megakaryocytic Leukemia in a Dog
Veterinary Pathology, 1978Most leukemias of dogs involve neutrophilic precursors. Monocytic leukemia is less common and only single cases of basophilic, megakaryocytic and erythroid leukemia in the canine species have been recorded [7]. A case of megakaryocytic leukosis of questionable neoplastic nature in a dog also has been described [lo].
M A, Holscher +3 more
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CD9 and megakaryocyte differentiation
Blood, 2001AbstractIt is shown that the tetraspanin CD9 has a complex pattern of distribution in hematopoietic cells and is heterogeneously expressed on human bone marrow CD34+ cells. CD34highCD38lowThy1+ primitive progenitors are contained in the population with intermediate CD9 expression, thus suggesting that CD9 expression may precede CD38 appearance.
D, Clay +7 more
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The origin of the megakaryocyte
Nature Cardiovascular Research, 2022Kellie R. Machlus, Eric Boilard
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Megakaryocyte endomitosis: A review
The International Journal of Cell Cloning, 1990During the early stages of their differentiation, megakaryocytes become polyploid through repeated DNA replication and endomitotic cycles without cytokinesis. The molecular basis for the process of polyploidization remains unknown. This review summarizes available information on the cell biology of the process of endomitosis.
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The determination of megakaryocyte ploidy
The International Journal of Cell Cloning, 1990Methods which have been used to determine megakaryocyte ploidy in animals and humans are reviewed. Although the number of megakaryocyte nuclear units counted in bone marrow squashes is roughly proportional to ploidy, accurate determinations of DNA content require the use of microphotometry or flow cytometry.
J M, Paulus +2 more
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