Results 91 to 100 of about 8,227 (218)
Hybrid Models in Erythropoiesis and in Megakaryopoiesis [PDF]
Mathematical Modelling of Natural Phenomena, 2015 Summary: Hematopoiesis is a complex process which results in production of erythrocytes, platelets and white blood cells from pluripotent stem cells located in the bone marrow. We will present hybrid models of hematopoiesis and will use them to study the lineage choice of bipotent erythro-megakaryocytic progenitors and erythroid lineage of ...
Eymard, N., Kurbatova, P.
openaire +2 more sources
British Journal of Haematology, Volume 208, Issue 2, Page 784-788, February 2026.Left panel: Scheme of the XPAG‐immune thrombocytopenia trial. The dexamethasone (DEX) arm consisted of DEX 40 mg/day for days 1–4 for one to three cycles every 28 days to a maximum of 12 weeks, cycles 2 + 3 were optional. Patients randomised to eltrombopag (ETB) + DEX received eltrombopag in combination with a short course of high‐dose DEX beginning on
Paul Schmidt‐Barbo +24 more
wiley +1 more source
What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog
Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson +5 more
wiley +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.ABSTRACT Background Alterations in hematological parameters in SARS‐CoV‐2 infection may contribute to disease severity and poor outcomes. This study reports the hematological profile of COVID‐19 patients. Methods This was a cross‐sectional study involving 169 confirmed COVID‐19 patients conducted at Sunyani Teaching Hospital between January and August,
Charles Nkansah +2 more
wiley +1 more source
Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation [PDF]
, 2014 The zinc finger transcriptional repressor Gfi-1b is essential for erythroid and megakaryocytic development in the embryo. Its roles in the maintenance of bone marrow erythropoiesis and thrombopoiesis have not been defined.
Amzallag, Arnaud +11 more
core +1 more source
Scientific Reports, 2023 Thrombocytopenia is a major and fatal complication in patients with acute myeloid leukemia (AML), which results from disrupted megakaryopoiesis by leukemic niche and blasts.
Ai Gao +10 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.ABSTRACT Glanzmann thrombasthenia (GT) is an inherited hemorrhagic disorder characterised by impaired platelet functions, manifested clinically as spontaneous bleeding. It is usually inherited in an autosomal recessive manner. Platelet dysfunction in patients with GT is caused by quantitative and/or qualitative deficiencies in αIIbβ3, which result from
Jiao Wu +14 more
wiley +1 more source
Absence of acquired copy number neutral loss of heterozygosity (CN-LOH) of chromosome 7 in a series of 10 patients with Shwachman-Diamond syndrome [PDF]
, 2014 We report that acquired copy number neutral loss of heterozygosity (CN-LOH) of chromosome 7 was not identified in a series of 10 patients with Shwachman\u2013Diamond syndrome (SDS)
Cannioto, Z. +12 more
core +1 more source
A Mad(2) modification modulating megakaryopoiesis [PDF]
Journal of Experimental Medicine, 2014 ![Figure][1] Insight from Adam Goldfarb Megakaryocytes, the rare platelet-producing cells within the bone marrow, undergo an unusual developmental transition from early mitotic proliferation to endomitosis associated with polyploidization and enlargement.
openaire +2 more sources
Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines
eJHaem, Volume 6, Issue 6, December 2025.ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer +6 more
wiley +1 more source