Results 71 to 80 of about 4,754 (217)

The Safety and Efficacy of an Immunomodulator Garlic‐Based Cream (LeishG1) for Treating Uncomplicated Cutaneous Leishmaniasis: A Single‐Blind, Multi‐Center Study

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) is a major problem in developing nations, particularly in the Middle East. Novel herbal treatment options may provide a safe alternative associated with favorable outcomes in CL lesion healing.
Fatemeh Emadi, Zohreh Khodashenas, Azadeh Rashidi, Ali Khamesipour, Mehdi Zaboli, Mehri Ghafourian, Mohammad Mehdi Naghizadeh, Fatemeh Tuserkani, Tooba Ghazanfari   +8 more
wiley   +1 more source

Critically Appraised Topic on Canine Leishmaniosis: Does Treatment with Antimonials and Allopurinol Have the Same Clinical and Clinicopathological Efficacy as Treatment with Miltefosine and Allopurinol, after One Month of Treatment?

Veterinary Sciences
The treatment of canine leishmaniosis commonly involves meglumine antimoniate with allopurinol or miltefosine with allopurinol. This study aims to compare the clinical and clinicopathological efficacy at 28–30 days of conventional dosing regimens for ...
Marina García, Lluís Ferrer, Laura Ordeix   +2 more
doaj   +1 more source

Nueva estrategia terapéutica basada en nanotecnología contra leishmaniasis tegumentaria en Ecuador = New pharmacological strategy based in nanotechnology against cutaneous leishmaniasis in Ecuador [PDF]

, 2010
Leishmaniasis is an endemic disease with wide distribution in tropical and subtropical regions around the world. It is considered that the incidence of this infection would be increased due to the progressive urbanization process which consequence is the
Loayza Villa, María Fernanda
core  

Mitochondrial Dysfunction Induced by a Novel Salicylate‐Based 1,2,3‐Triazole Salt With Potent Antileishmanial Activity

Chemical Biology &Drug Design, Volume 106, Issue 6, December 2025.
A novel salicylate‐based 1,2,3‐triazole salt was synthesized and demonstrated potent and selective activity against Leishmania amazonensis. The most active compound induced mitochondrial dysfunction without hemolytic effects. In silico analyses also suggested favorable pharmacokinetic properties and oral bioavailability.
Bruno A. De Oliveira, Ari Sérgio de Oliveira Lemos, João Pedro Reis Costa Bastos, Luciana Maria Ribeiro Antinarelli, Ana Luiza Ribeiro de Freitas, Raissa Guedes Mattosinhos Ribeiro, Adolfo Firmino da Silva Neto, Elaine Soares Coimbra, Adilson David Da Silva   +8 more
wiley   +1 more source

American tegumentary leishmaniasis: severe side effects of pentavalent antimonial in a patient with chronic renal failure [PDF]

Anais Brasileiros de Dermatologia, 2019
: Pentavalent antimonials are the first-line drug treatment for American tegumentary leishmaniasis. We report on a patient with chronic renal failure on hemodialysis who presented with cutaneous lesions of leishmaniasis for four months.
Sílvio Alencar Marques, Maira Renata Merlotto, Paulo Müller Ramos, Mariangela Esther Alencar Marques   +3 more
doaj   +1 more source

Four Cutaneous Leishmaniosis Case Resistant to Meglumine Antimoniate Treatment

Turkish Journal of Parasitology, 2014
The aim of the study was to treatment of cutaneous leishmaniasis caused by meglumine antimoniate resistant Leishmania major with Lucilia sericata larvae.Samples obtained from patients'lesions were stained with Giemsa and examined under the microscope. The samples were also incubated to Novy-Nicolle-McNeal (NNN) and Roswell Park Memorial Institute (RPMI)
Erdal, Polat, Zekayi, Kutlubay
openaire   +2 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Diagnostic Challenges in Visceral Leishmaniasis in a 17‐Month‐Old Female: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Visceral leishmaniasis is an uncommon infectious disease. In this report, we present a case of VL in a 17‐month‐old child who presented with a fever and splenomegaly. After the patient failed to respond to several courses of antibiotics, a bone marrow aspirate confirmed the definitive diagnosis of VL, which was successfully treated with ...
Ahmed Sheikh Sobeh, Manal Soufan, Tasneem Sarakbi, Alaa Jaddouh, Feras Alharroush   +4 more
wiley   +1 more source

Travelers With Cutaneous Leishmaniasis Cured Without Systemic Therapy [PDF]

, 2017
Guidelines recommend wound care and/or local therapy as first-line treatment for cutaneous leishmaniasis. An analysis of a referral treatment program in 135 travelers showed that this approach was feasible in 62% of patients, with positive outcome in 83%
Abergel, H., Alcaraz, I., Amoric, J. C., Ancelle, T., Baccard, M., Barthelme, D., Begon, E., Belon, M., Belot, G., Beneton-Benhard, N., Bezier, M., Bodak, N., Bougnoux, M. E., Bourgeois, A., Bourrat, E., Broissin, M., Buffet, P. A., Busquet, P., Caby, F., Canestri, A., Carpentier, O., Carre, D., Caumes, E., Celerier, P., Clabaut, A., Colin De Verdiere, N., Consigny, P. H., Cordoliani, F., Cuchet, E., Dallot, A., Datry, A., Dellestable, P., Dumortier, C., Dupin, N., Dupuis De Fonclare, A. L., Durupt, F., El Samad, Y., Foulet, F., Galezowsky, M. F., Gangneux, J. P., Gener, G., Gounod, N., Grogl, M., Grossetête, G., Guillemot, F., Hadj Rabia, S., Hamel, D., Herve, A., Hillion, B., Hochedez, P., Hope Rapp, E., Janier, M., Jouan, M., Jouy, L., Juillard, C., Karam, S., Kendjo, E., Kieffer, C., Lachaud, L., Laffitte, E., Le Duc, D., Lesens, O., Levy, A., Marty, P., Maubon, D., Maus, E., Mazier, D., Mechai, F., Menot, E., Meunier, L., Moisson, Y. F., Moraillon, I., Morizot, G., Mouly, F., Mouri, O., Ortoli, J. C., Paugam, A., Pelletier-Cunat, S., Perrin, P., Petit, A., Pomares, C., Pérignon, A., Ranque, B., Ravel, C., Rebauder, S., Regner, S., Roch, N., Rogeaux, O., Rozembaum, F., Salle, V., Schneider, P., Strady, C., Tamarin, J. M., Thellier, M., Timsit, F., Verdon, R., Vray, M., Wolter-Desfosses, M.   +97 more
core  

Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment [PDF]

, 2016
Background: The objective of this study was to evaluate and compare the evolution of the profile currently recommended by the International Renal Interest Society (IRIS) (sCr, UPC and sSDMA) with a panel of other different kidney biomarkers during ...
Cerón Madrigal, José Joaquín, Garcia-Martinez, Juan Diego, Martínez-Subiela, Silvia, Pardo-Marín, Luis, Pastor Milán, Josep, Segarra, Sergi, Tvarijonaviciute, Asta   +6 more
core   +2 more sources