Results 51 to 60 of about 16,852 (174)

Proteome of oocyte spindle identifies Ccdc69 regulates spindle assembly like “band-tightening spell”

open access: yesCellular and Molecular Life Sciences
Meiotic spindle is an intricate structure and required for chromosome segregation and the proper meiotic progression during oocyte maturation, and its function is regulated by a complex network of proteins located at spindle and its peripheral region ...
Jia-Ni Guo   +12 more
doaj   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong   +7 more
wiley   +1 more source

Análise invasiva e não invasiva do fuso meiótico de oócitos humanos obtidos de ciclos estimulados: dados preliminares Invasive and noninvasive analysis of the meiotic spindle of human oocytes obtained from stimulate cycles: preliminary results

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2012
OBJETIVOS: Avaliar a concordância entre as técnicas de microscopia de polarização e microscopia confocal na avaliação do fuso meiótico de oócitos humanos maturados in vivo.
Luciana Azôr Dib   +5 more
doaj   +1 more source

Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes

open access: yesNature Communications, 2020
Mammalian oocytes divide asymmetrically during meiotic maturation. Here, the authors show that spindle movement away from oocyte center depends on actin filaments nucleated from the spindle periphery pushing against surrounding mitochondria, which ...
Xing Duan   +12 more
doaj   +1 more source

Bisphenol B Exposure Disrupts Mouse Oocyte Meiotic Maturation in vitro Through Affecting Spindle Assembly and Chromosome Alignment

open access: yesFrontiers in Cell and Developmental Biology, 2020
Bisphenol B (BPB), a substitute of bisphenol A (BPA), is widely used in the polycarbonate plastic and resins production. However, BPB proved to be not a safe alternative to BPA, and as an endocrine disruptor, it can harm the health of humans and animals.
Shou-Xin Zhang   +9 more
doaj   +1 more source

Embryonic development of the Mediterranean starfish Hacelia attenuata

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Starfish play essential ecological roles as predators and ecosystem regulators; however, detailed developmental descriptions exist for only a handful of species, none of which are from the Mediterranean Sea. Results In this study, we provide the first full account of the development of the Mediterranean starfish Hacelia attenuata ...
Silvia Caballero‐Mancebo   +3 more
wiley   +1 more source

Cdc6 is required for meiotic spindle assembly in Xenopus oocytes [PDF]

open access: yesCell Cycle, 2012
During the maturation of Xenopus oocytes, Cdc6 expression is necessary to establish replication competence to support early embryonic DNA replication. However, Cdc6 is expressed before the completion of MI, at a time when its function as a replication factor is not required, suggesting additional roles for Cdc6 in meiosis.
Yadushyla, Narasimhachar   +3 more
openaire   +2 more sources

MRE11 orchestrates porcine oocyte meiotic progression by modulating the spindle assembly checkpoint

open access: yesFrontiers in Cell and Developmental Biology
IntroductionMre11 is a multisubunit nuclease involved in DNA repair, and its dysfunction often causes DNA damage sensitivity, genomic instability, telomere shortening, and aberrant meiosis.
Dandan Zhang   +8 more
doaj   +1 more source

Two near‐complete assemblies reveal R‐subgenome structural and centromeric divergence associated with reproductive isolation in hexaploid triticale

open access: yesiMeta, EarlyView.
We present two near‐complete triticale genome assemblies and perform pan‐centromere analyses across >200 haplotypes from parental species, synthetic allopolyploids, cultivars, and 337 resequenced accessions, revealing a shared chromatin framework underlying functional centromeres in all three subgenomes, where wheat‐ and rye‐derived CENH3 co‐occupy ...
Yang Liu   +7 more
wiley   +1 more source

B-type nuclear lamin and the nuclear pore complex Nup107-160 influences maintenance of the spindle envelope required for cytokinesis in Drosophila male meiosis

open access: yesBiology Open, 2016
In higher eukaryotes, nuclear envelope (NE) disassembly allows chromatin to condense and spindle microtubules to access kinetochores. The nuclear lamina, which strengthens the NE, is composed of a polymer meshwork made of A- and B-type lamins.
Daisuke Hayashi   +3 more
doaj   +1 more source

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