Results 41 to 50 of about 110,429 (168)

Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes [PDF]

open access: yes, 2007
The spindle checkpoint delays anaphase onset until all chromosomes have attached in a bi-polar manner to the mitotic spindle. Mad and Bub proteins are recruited to unattached kinetochores, and generate diffusible anaphase inhibitors.
Rischitor, Patricia E   +8 more
core   +2 more sources

spindle assembly trajectories

open access: yes, 2022
Morphological growth trajectories of meiotic spindle self-organization in Xenopus egg extracts 
Yuta Shimamoto (13041201)   +1 more
core   +1 more source

WAPL orchestrates porcine oocyte meiotic progression via control of spindle assembly checkpoint activity

open access: yesReproductive Biology and Endocrinology, 2021
Background In mitotic cells, WAPL acts as a cohesin release factor to remove cohesin complexes from chromosome arms during prophase to allow the accurate chromosome segregation in anaphase.
Changyin Zhou   +3 more
doaj   +1 more source

Importin α and vNEBD Control Meiotic Spindle Disassembly in Fission Yeast

open access: yesCell Reports, 2018
Summary: In metazoans, the nuclear envelope (NE) breakdown (NEBD) occurs during “open” mitosis and meiosis. In the fission yeast Schizosaccharomyces pombe, the mitosis and the first meiotic division (MI) are “closed,” during which the NE is maintained ...
Ignacio Flor-Parra   +5 more
doaj   +1 more source

C. elegans CLASP/CLS-2 negatively regulates membrane ingression throughout the oocyte cortex and is required for polar body extrusion.

open access: yesPLoS Genetics, 2020
The requirements for oocyte meiotic cytokinesis during polar body extrusion are not well understood. In particular, the relationship between the oocyte meiotic spindle and polar body contractile ring dynamics remains largely unknown.
Aleesa J Schlientz, Bruce Bowerman
doaj   +1 more source

Disrupted meiotic spindle configurations.

open access: yes, 2013
Note: Meiotic spindle configurations were evaluated by immunofluorescence analysis of individual oocytes that were fixed at the end of an 18-hour culture. Spindle microtubules were detected with anti-Ac-tubulin, and the DNA was labeled with DAPI.
Zhong-Hong Wu (299091)   +9 more
core   +1 more source

Revised and Improved Procedure for Immunolocalization of Male Meiotic Chromosomal Proteins and Spindle in Plants without the Use of Enzymes

open access: yesPlants, 2018
Immunolocalization studies to visualize the distribution of proteins on meiotic chromosomes have become an integral part of studies on meiosis in the model organism Arabidopsis thaliana.
Kuntal De   +2 more
doaj   +1 more source

Cytoplasmic determination of meiotic spindle size revealed by a unique inter-species germinal vesicle transfer model [PDF]

open access: yes, 2016
Spindle sizes are different in diverse species and cell types. In frogs, the meiotic spindle size is positively correlated with the egg cell volume. Across species, relatively small mouse oocytes (70–80 μm) have a relatively large spindle while larger ...
Wang, Zhong-Wei   +4 more
core   +1 more source

Simulated microgravity compromises mouse oocyte maturation by disrupting meiotic spindle organization and inducing cytoplasmic blebbing. [PDF]

open access: yesPLoS ONE, 2011
In the present study, we discovered that mouse oocyte maturation was inhibited by simulated microgravity via disturbing spindle organization. We cultured mouse oocytes under microgravity condition simulated by NASA's rotary cell culture system, examined ...
Changli Wu   +7 more
doaj   +1 more source

Melatonin Protects Against Mdivi-1-Induced Abnormal Spindle Assembly and Mitochondrial Superoxide Production During Porcine Oocyte Maturation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mitochondrial division inhibitor 1 (Mdivi-1) reportedly provides a close connection between oocyte maturation and mitochondrial function in pigs. N-acetyl-5-methoxy-tryptamine (melatonin) is known to be a representative antioxidant with the ability to ...
Seul-Gi Yang   +11 more
doaj   +1 more source

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