Results 21 to 30 of about 16,852 (174)

Katanin controls mitotic and meiotic spindle length [PDF]

The Journal of Cell Biology, 2006
Accurate control of spindle length is a conserved feature of eukaryotic cell division. Lengthening of mitotic spindles contributes to chromosome segregation and cytokinesis during mitosis in animals and fungi. In contrast, spindle shortening may contribute to conservation of egg cytoplasm during female meiosis.
McNally, Karen, Audhya, Anjon, Oegema, Karen, McNally, Francis J.   +3 more
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Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes. [PDF]

PLoS ONE, 2008
Formation of female gametes requires acentriolar spindle assembly during meiosis. Mitotic spindles organize from centrosomes and via local activation of the RanGTPase on chromosomes.
Stéphane Brunet, Julien Dumont, Karen W Lee, Kazuhisa Kinoshita, Pascale Hikal, Oliver J Gruss, Bernard Maro, Marie-Hélène Verlhac   +7 more
doaj   +1 more source

OsMTOPVIB is required for meiotic bipolar spindle assembly [PDF]

Proceedings of the National Academy of Sciences, 2019
Significance The organization of microtubules into a bipolar spindle is essential for chromosome segregation. Both centrosome and chromatin-dependent spindle assembly mechanisms are well studied in animals; however, the mechanism of bipolar spindle assembly in plant meiosis remains unclear.
Zhihui Xue, Changzhen Liu, Wenqing Shi, Yongjie Miao, Yi Shen, Ding Tang, Yafei Li, Aiqing You, Yunyuan Xu, Kang Chong, Zhukuan Cheng   +10 more
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Clathrin is essential for meiotic spindle function in oocytes [PDF]

Reproduction, 2010
Abstract In the mammalian ovary, oocytes are arrested at prophase of meiosis I until a hormonal stimulus triggers resumption of meiosis. During the subsequent meiotic maturation process, which includes completion of the first meiotic division and formation of the second metaphase spindle, oocytes acquire competence for fertilization ...
Hölzenspies, J.J., Roelen, B.A.J., Colenbrander, B., Romijn, R.A.P., Hemrika, W., Stoorvogel, W., van Haeften, T.   +6 more
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Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage.

PLoS Genetics, 2023
To prevent chromosome mis-segregation, a surveillance mechanism known as the spindle checkpoint delays the cell cycle if kinetochores are not attached to spindle microtubules, allowing the cell additional time to correct improper attachments.
Anne MacKenzie, Victoria Vicory, Soni Lacefield   +2 more
doaj   +1 more source

Aurora kinase A is essential for meiosis in mouse oocytes.

PLoS Genetics, 2021
The Aurora protein kinases are well-established regulators of spindle building and chromosome segregation in mitotic and meiotic cells. In mouse oocytes, there is significant Aurora kinase A (AURKA) compensatory abilities when the other Aurora kinase ...
Cecilia S Blengini, Patricia Ibrahimian, Michaela Vaskovicova, David Drutovic, Petr Solc, Karen Schindler   +5 more
doaj   +1 more source

Meiotic spindle assembly and chromosome segregation in oocytes [PDF]

Journal of Cell Biology, 2016
Oocytes accumulate maternal stores (proteins, mRNAs, metabolites, etc.) during their growth in the ovary to support development after fertilization. To preserve this cytoplasmic maternal inheritance, they accomplish the difficult task of partitioning their cytoplasm unequally while dividing their chromosomes equally.
Bennabi, Isma, Terret, Marie-Emilie, Verlhac, Marie-Hélène   +2 more
openaire   +3 more sources

Structure of the meiotic spindle [PDF]

The Journal of Cell Biology, 2007
![Graphic][1] Fluorescently labeled tubulin monomers within meiotic spindle filaments are seen as speckles whose motion can be tracked. KAPOOR/MACMILLAN The meiotic spindle is made up of shorter microtubules than previously believed, suggest results from Ge Yang, Gaudenz Danuser (
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Bipolar meiotic spindle formation without chromatin [PDF]

Current Biology, 1998
Establishing a bipolar spindle is an early event of mitosis or meiosis. In somatic cells, the bipolarity of the spindle is predetermined by the presence of two centrosomes in prophase. Interactions between the microtubules nucleated by centrosomes and the chromosomal kinetochores enable the formation of the spindle. Non-specific chromatin is sufficient,
Brunet, Stéphane, Polanski, Zbigniev, Verlhac, Marie-Hélène, Kubiak, Jacek, Maro, Bernard   +4 more
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A bouquet for meiotic spindle [PDF]

The Journal of Cell Biology, 2007
![][1] A burst of dissociation (left to right) of telomeres (green) from the SPB (red) may set up meiotic spindles. COOPER/ELSEVIER During early meiosis, telomeres gather at the nuclear membrane, forming a structure of mysterious function dubbed the telomere bouquet.
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