Results 81 to 90 of about 16,852 (174)

From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics

Advanced Science, Volume 13, Issue 41, 22 July 2026.
Mechanical properties of the oocyte are increasingly recognized as critical determinants of meiotic success and developmental potential. How actomyosin remodeling controls oocyte mechanics, how these properties are altered in pathological conditions, and how they could serve as markers in reproductive medicine are examined.
Anastasia Shihabi, Rose Bulteau, Lucie Barbier, Marie‐Emilie Terret   +3 more
wiley   +1 more source

The Landscape of BRCA1‐Associated Post‐Translational Modifications

Cell Biology International, Volume 50, Issue 7, July 2026.
ABSTRACT The BRCA1‐BARD1 complex is a vital protein that promotes homologous recombination, acting through its E3 ubiquitin ligase activity. Although ubiquitination remains its only confirmed enzymatic function, emerging evidence suggests that the complex influences a broad range of post‐translational modifications (PTMs), including methylation ...
Nethma Hewa Waduge, Junhua Xiao, Gregory M. Davis   +2 more
wiley   +1 more source

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

Advanced Science
As a major component of the cytoskeleton, intermediate filaments are generally considered to play a supporting role in mitotic cells. They also take part in the regulation of cell motility, proliferation, differentiation, and apoptosis.
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
doaj   +1 more source

PCH-2 collaborates with CMT-1 to proofread meiotic homolog interactions.

PLoS Genetics, 2020
The conserved ATPase, PCH-2/TRIP13, is required during both the spindle checkpoint and meiotic prophase. However, its specific role in regulating meiotic homolog pairing, synapsis and recombination has been enigmatic.
Stefani Giacopazzi, Daniel Vong, Alice Devigne, Needhi Bhalla   +3 more
doaj   +1 more source

Ipl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis.

PLoS ONE, 2013
Cells coordinate spindle formation with DNA repair and morphological modifications to chromosomes prior to their segregation to prevent cell division with damaged chromosomes.
Louise Newnham, Philip W Jordan, Jesus A Carballo, Sonya Newcombe, Eva Hoffmann   +4 more
doaj   +1 more source

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science
The cytoskeleton is composed of microtubules, microfilaments, and intermediate filaments in cells. While the functions of microtubules and microfilaments have been well elucidated, the roles of intermediate filaments and associated proteins remain ...
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
doaj   +1 more source

Multiple requirements of PLK1 during mouse oocyte maturation.

PLoS ONE, 2015
Polo-like kinase 1 (PLK1) orchestrates multiple events of cell division. Although PLK1 function has been intensively studied in centriole-containing and rapidly cycling somatic cells, much less is known about its function in the meiotic divisions of ...
Petr Solc, Tomoya S Kitajima, Shuhei Yoshida, Adela Brzakova, Masako Kaido, Vladimir Baran, Alexandra Mayer, Pavlina Samalova, Jan Motlik, Jan Ellenberg   +9 more
doaj   +1 more source

To Make a Long Spindle Short: Nuclear Envelope Breakdown during Meiosis

Cell Reports, 2018
In fission yeast, the nuclear envelope (NE) remains intact during mitosis and meiosis I but is compromised during meiosis II. In this issue of Cell Reports, Flor-Parra et al.
Joseph M. Varberg, Sue L. Jaspersen
doaj   +1 more source

NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.

PLoS ONE, 2017
NIMA-related kinase 1 (NEK1) is a serine/threonine and tyrosine kinase that is highly expressed in mammalian germ cells. Mutations in Nek1 induce anemia, polycystic kidney and infertility.
Miguel A Brieño-Enríquez, Stefannie L Moak, J Kim Holloway, Paula E Cohen   +3 more
doaj   +1 more source

MEIOTIC SPINDLE PLAQUES IN SACCHAROMYCES CEREVISIAE [PDF]

The Journal of Cell Biology, 1972
J B, Peterson, R H, Gray, H, Ris
openaire   +2 more sources