Results 81 to 90 of about 110,429 (168)
, 2021 A Drosophila gene encoding a novel zinc-finger protein, Meics, was cloned using a monoclonal antibody. The predicted amino acid sequence contains 12 zinc-finger motifs of the C2H2-type. During spermatogenesis, Meics distributes intranuclearly at pre- and
Goday, Clara +3 more
core +1 more source
A Taz1- and Microtubule-Dependent Regulatory Relationship between Telomere and Centromere Positions in Bouquet Formation Secures Proper Meiotic Divisions. [PDF]
PLoS Genetics, 2016 During meiotic prophase, telomeres cluster, forming the bouquet chromosome arrangement, and facilitate homologous chromosome pairing. In fission yeast, bouquet formation requires switching of telomere and centromere positions.
Kazuhiro Katsumata +8 more
doaj +1 more source
Advanced Science, Volume 13, Issue 59, 23 October 2026.SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source
Latrunculin A delays anaphase onset in fission yeast by disrupting an ase1-independent pathway controlling mitotic spindle stability [PDF]
, 2008 It has been proposed previously that latrunculin A, an inhibitor of actin polymerization, delays the onset of anaphase by causing spindle misorientation in fission yeast.
Meadows, John C., Millar, Jonathan B. A.
core +1 more source
Spindle assembly timelapse with monastrol
, 2022 Timelapse images of meiotic spindle self-organization in Xenopus egg extracts supplemented with monastrol (red: tubulin; green: DNA)
Yuta Shimamoto (13041201) +1 more
core +1 more source
Cytoskeleton, Volume 83, Issue 10, Page 779-794, October 2026.ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts
, 2011 Female meiotic spindles in many organisms form in the absence of centrosomes, the organelle typically associated with microtubule (MT) nucleation.
Ronald D. Vale +3 more
core +1 more source
Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A [PDF]
, 2013 Anaphase central spindle formation is controlled by the microtubule-stabilizing factor PRC1 and the kinesin KIF4A. We show that an MKlp2-dependent pool of Aurora B at the central spindle, rather than global Aurora B activity, regulates KIF4A accumulation
Erich A. Nigg +11 more
core +1 more source
Spindle assembly trajectories with augmin
, 2022 Morphological growth trajectories of meiotic spindle self-organization in Xenopus egg extracts supplemented with purified augmin ...
Yuta Shimamoto (13041201) +1 more
core +1 more source
Multiple Duties for Spindle Assembly Checkpoint Kinases in Meiosis
Frontiers in Cell and Developmental Biology, 2017 Cell division in mitosis and meiosis is governed by evolutionary highly conserved protein kinases and phosphatases, controlling the timely execution of key events such as nuclear envelope breakdown, spindle assembly, chromosome attachment to the spindle ...
Adele L. Marston +2 more
doaj +1 more source