Results 91 to 100 of about 18,808 (211)

Symmetrical Shape of the Meiotic Spindle is Dynamically Balanced [PDF]

Biophysical Journal, 2013
Meiotic spindle assembly is critical for achieving accurate chromosome segregation. The spindle mainly consists of microtubules and molecular motors. Recent studies have suggested that bipolar spindle formation requires the force balance sustained by molecular motors and polymerization-depolymerization dynamics of microtubules.
Suzuki, Kazuya, Takagi, Jun, Itabashi, Takeshi, Ishiwata, Shin'ichi   +3 more
openaire   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

Nature Communications, 2020
Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase
Zhe Wei, Jessica Greaney, Wei-Guo Nicholas Loh, Hayden Anthony Homer   +3 more
doaj   +1 more source

SGO1 and SGO2 are Associated With Disease Progression and an Immunosuppressive Microenvironment in Papillary Renal Cell Carcinoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Shugoshin proteins SGO1 and SGO2 regulate chromosome cohesion and segregation during mitosis and meiosis, and their aberrant expression is implicated in several cancers. However, the mechanistic involvement of these two proteins in papillary renal cell carcinoma (KIRP) and their contribution to immune evasion remains unclear ...
Han Fu, Alisherjon Ibrohimov, Hao Zheng, Yue Pan, Jieyu Hu, Banzhan Ruan, Hang Huang, Shi Li   +7 more
wiley   +1 more source

Generative Cell Division, but Not Early Nuclear Reorganization, Requires Transcriptional Reactivation During Pollen Tube Growth

Plant Direct, Volume 10, Issue 6, June 2026.
ABSTRACT Bicellular pollen often enters a desiccated state wherein development is temporarily arrested, enabling long‐term survival while maintaining the capacity for rapid activation upon hydration. Although the generative cell in mature pollen of Lilium species is known to have completed DNA replication, its precise cell‐cycle status and the ...
Mio K. Shibuta, Aina Komatsu, Tsugumi Aso   +2 more
wiley   +1 more source

A role for environmental niche divergence in the rapid radiation of Nicotiana section Suaveolentes (Solanaceae)

TAXON, Volume 75, Issue 3, June 2026.
Abstract Nicotiana sect. Suaveolentes is a group that has undergone recent and rapid radiation, a clade that originated ca. six million years ago and has since rapidly speciated throughout Australia, with a few taxa on Pacific Islands and one in Namibia (Africa). Post‐tetraploidisation, species in N. sect.
Charlotte Phillips, Maïté Guignard, Luiz A. Cauz‐Santos, Maarten J.M. Christenhusz, Leylson Ferreira de Araújo, Felipe Nollet, Mark W. Chase, Steven Dodsworth   +7 more
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, Volume 13, Issue 29, 22 May 2026.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Cytoplasmic determination of meiotic spindle size revealed by a unique inter-species germinal vesicle transfer model [PDF]

, 2016
Spindle sizes are different in diverse species and cell types. In frogs, the meiotic spindle size is positively correlated with the egg cell volume. Across species, relatively small mouse oocytes (70–80 μm) have a relatively large spindle while larger ...
Wang, Zhong-Wei, Sun, Qing-Yuan, Zhang, Guang-Li, Schatten, Heide, Carroll, John   +4 more
core   +1 more source

Introgression of a Terminal Segment From Chromosome 3S of Festuca mairei Increases Drought Resistance of Lolium perenne

Food and Energy Security, Volume 15, Issue 3, May/June 2026.
ABSTRACT Due to climate change, the requirement for increased resilience by grassland systems to onsets of ever‐increasing drought stresses makes the development of drought‐resistant forage crops a priority for future food and energy security. Novel ×Festulolium (Festuca × Lolium) cultivars offer unique opportunities to combine complementary traits ...
David Kopecký, Vladimír Černoch, Martin Duchoslav, Mike W. Humphreys   +3 more
wiley   +1 more source