Results 101 to 110 of about 18,808 (211)

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

Advanced Science
As a major component of the cytoskeleton, intermediate filaments are generally considered to play a supporting role in mitotic cells. They also take part in the regulation of cell motility, proliferation, differentiation, and apoptosis.
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
doaj   +1 more source

Ipl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis.

PLoS ONE, 2013
Cells coordinate spindle formation with DNA repair and morphological modifications to chromosomes prior to their segregation to prevent cell division with damaged chromosomes.
Louise Newnham, Philip W Jordan, Jesus A Carballo, Sonya Newcombe, Eva Hoffmann   +4 more
doaj   +1 more source

PCH-2 collaborates with CMT-1 to proofread meiotic homolog interactions.

PLoS Genetics, 2020
The conserved ATPase, PCH-2/TRIP13, is required during both the spindle checkpoint and meiotic prophase. However, its specific role in regulating meiotic homolog pairing, synapsis and recombination has been enigmatic.
Stefani Giacopazzi, Daniel Vong, Alice Devigne, Needhi Bhalla   +3 more
doaj   +1 more source

F-actin prevents interaction between sperm DNA and the oocyte meiotic spindle in C. elegans [PDF]

, 2017
Fertilization occurs during female meiosis in most animals, which raises the question of what prevents the sperm DNA from interacting with the meiotic spindle.
Marin, Harold C, Francis J. McNally, Panzica, Michelle T, Michelle T. Panzica, Anne-Cecile Reymann, Harold C. Marin, McNally, Francis J, Reymann, Anne-Cecile   +7 more
core   +1 more source

Oocyte Meiotic Spindle Assembly in Caenorhabditis Elegans [PDF]

, 2014
As in many organisms, Caenorhabditis elegans oocytes assemble bipolar meiotic spindles in the absence of centrosomes. While the assembly of the mitotic spindle in C.
Connolly, Amy
core  

On the origin of trisomy 21 Down syndrome [PDF]

, 2008
Background: Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability.
Nikos Papadogiannakis, Maj A Hultén, Papadogiannakis, Nikos, Westgren, Magnus, Jonsson, Anna Maria, Tankimanova, Maira, Patel, Suketu D., Iwarsson, Erik, Maira Tankimanova, Anna Jonsson, Magnus Westgren, Erik Iwarsson, Hultén, Maj A., Suketu D Patel   +13 more
core   +1 more source

Meiotic nuclear divisions in budding yeast require PP2ACdc55-mediated antagonism of Net1 phosphorylation by Cdk [PDF]

, 2011
During meiosis, one round of deoxyribonucleic acid replication is followed by two rounds of nuclear division. In Saccharomyces cerevisiae, activation of the Cdc14 early anaphase release (FEAR) network is required for exit from meiosis I but does not lead
Sourav Sarkar, Millar, Jonathan B.A., Kerr, Gary W., Tibbles, Katherine L., Prakash Arumugam, Kerr, Gary, Gary W. Kerr, Sarkar, Sourav, Millar, Jonathan B. A., Katherine L. Tibbles, Jonathan B.A. Millar, Arumugam, Prakash, Mark Petronczki, Petronczki, Mark   +13 more
core   +1 more source

The muntjac spindle staining assay: An investigation of the ability of this assay to detect potential aneuploidy inducing agents

, 1988
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.An assay using muntjac fibroblasts in conjunction with a differential spindle and chromosome stain was developed and evaluated for its ability to detect ...
Pascoe, Sally Ann
core  

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science
The cytoskeleton is composed of microtubules, microfilaments, and intermediate filaments in cells. While the functions of microtubules and microfilaments have been well elucidated, the roles of intermediate filaments and associated proteins remain ...
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
doaj   +1 more source

CDK-1 inhibits meiotic spindle shortening and dynein-dependent spindle rotation in C. elegans

, 2011
In animals, the female meiotic spindle is positioned at the egg cortex in a perpendicular orientation to facilitate the disposal of half of the chromosomes into a polar body.
Francis J. McNally, Marina L. Ellefson
core   +1 more source