Results 121 to 130 of about 18,808 (211)

Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts

open access: yes, 2011
Female meiotic spindles in many organisms form in the absence of centrosomes, the organelle typically associated with microtubule (MT) nucleation.
Ronald D. Vale   +3 more
core   +1 more source

Inward transport of organelles drives outward migration of the spindle during C. elegans meiosis

open access: yesCell Reports
Summary: Cortical positioning of the meiotic spindle within an oocyte is required to expel chromosomes into polar bodies to generate a zygote with the correct number of chromosomes. In C.
Alma P. Aquino   +9 more
doaj   +1 more source

Rac Activity Is Polarized and Regulates Meiotic Spindle Stability and Anchoring in Mammalian Oocytes

open access: yes, 2007
SummaryMammalian meiotic divisions are asymmetrical and generate a large oocyte and two small polar bodies. This asymmetry results from the anchoring of the meiotic spindle to the oocyte cortex and subsequent cortical reorganization, but the mechanisms ...
Halet, Guillaume, Carroll, John
core   +1 more source

NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes

open access: yesReproductive Biology and Endocrinology
Background Neuroepithelial transforming gene 1 (NET1) is a RhoA subfamily guanine nucleotide exchange factor that governs a wide array of biological processes. However, its roles in meiotic oocyte remain unclear.
Shiwei Wang   +8 more
doaj   +1 more source

MEIOTIC SPINDLE PLAQUES IN SACCHAROMYCES CEREVISIAE [PDF]

open access: yesThe Journal of Cell Biology, 1972
J B, Peterson, R H, Gray, H, Ris
openaire   +2 more sources

NEDD1 is crucial for meiotic spindle stability and accurate chromosome segregation in mammalian oocytes

open access: yes, 2010
Defects in meiotic spindle structure contribute to chromosome segregation errors leading to genomic instability in oocytes and embryos upon fertilization. In this study, we analyzed the mechanisms that control spindle microtubule nucleation and stability
Viveiros, Maria M.   +5 more
core   +1 more source

Relationship between visualization of meiotic spindle in human oocytes and ICSI outcomes: a meta-analysis

open access: yes, 2009
The objective of this meta-analysis was to investigate the influence of meiotic spindle visualization in human oocytes on intracytoplasmic sperm injection (ICSI) outcomes. Search strategies included on-line Surveys of databases (MEDLINE, em BASE, Science
Pontes, Anaglória   +9 more
core   +1 more source

Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. [PDF]

open access: yesNat Commun, 2023
He S   +8 more
europepmc   +1 more source

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