Results 101 to 110 of about 169,076 (377)
Advanced Sustainable Systems, EarlyView.The insect‐microbe interplay fulfills a key ecological role involving the degradation of ligninocellulose biomass. This is coordinated by the secretion of different kinds of proteins, of which ligninolytic enzymes, such as laccases (Lacs), are of prime importance.
Michael Dare Asemoloye +11 more
wiley +1 more source
Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs
Pharmaceutics, 2020 Interactions between drugs and melanin pigment may have major impacts on pharmacokinetics. Therefore, melanin binding can modify the efficacy and toxicity of medications in ophthalmic and other disease of pigmented tissues, such as melanoma.
Laura Hellinen +5 more
doaj +1 more source
Shedding light on melanins within in situ human eye melanocytes using 2-photon microscopy profiling techniques. [PDF]
, 2019 Choroidal melanocytes (HCMs) are melanin-producing cells in the vascular uvea of the human eye (iris, ciliary body and choroid). These cranial neural crest-derived cells migrate to populate a mesodermal microenvironment, and display cellular functions ...
Cherepanoff, Svetlana +6 more
core
Melanin-Concentrating Hormone (MCH): Role in REM Sleep and Depression. [PDF]
, 2015 The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons of the lateral sector of the posterior hypothalamus and zona incerta.
Benedetto, Luciana +8 more
core +3 more sources
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Scientific Reports, 2020 The fate of melanin in the epidermis is of great interest due to its involvement in numerous physiological and pathological processes in the skin. Melanin localization can be assessed ex vivo and in vivo using its distinctive optical properties.
B. P. Yakimov +5 more
doaj +1 more source
Guttate leukoderma and acrokeratosis verruciformis of Hopf: a rare combination in Darier disease [PDF]
, 2020 A distinct Darier phenotype presenting with confetti-like hypopigmented macules was first described in 1965. Designated as "guttate leukoderma," this skin finding is a rarely-reported presentation of Darier disease.
Grossman, Shoshana K +4 more
core
Tailoring Synthetic Melanin Nanoparticles for Enhanced Photothermal Therapy.
ACS Applied Materials and Interfaces, 2019 Melanin and its synthetic analogs (i.e., polydopamine nanomaterials) are able to transform a near-infrared (NIR) light energy source to heat for the selective killing of cancer cells.
Peng Yang +9 more
semanticscholar +1 more source
Chemistry of Melanin. IV. Electron Micrography of Natural Melanins.
Experimental Biology and Medicine, 1947 Summary1. Melanin granules were obtained by differential centrifugation from the S-91 and Harding-Passey transplantable mouse melanomas, from the choroid, ciliary body and iris of the beef eye, and...
Albert J. Dalton +3 more
openaire +3 more sources
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
Advanced Science, EarlyView.In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao +12 more
wiley +1 more source