Results 51 to 60 of about 71,458 (290)

Structural analysis and spectroscopic characterization of melanin-alginate films

open access: yesChemical Physics Impact
In this work, we present the spectroscopic and structural analysis of synthetic melanin incorporated within alginate films. We propose a synthesis methodology for alginate films with different concentrations of melanin.
Lidia Elizabeth Verduzco-Grajeda   +4 more
doaj   +1 more source

Melanin-based structural coloration of birds and its biomimetic applications

open access: yesApplied Microscopy, 2021
Melanin has been a widely researched pigment by scientists for decades as it is undoubtedly the most ubiquitous and ancient pigment found in nature.
Deok-Jin Jeon   +3 more
doaj   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

open access: yesAdvanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang   +6 more
wiley   +1 more source

Role of Melanin Chemiexcitation in Melanoma Progression and Drug Resistance

open access: yesFrontiers in Oncology, 2020
Melanoma is the deadliest type of skin cancer. Human melanomas often show hyperactivity of nitric oxide synthase (NOS) and NADPH oxidase (NOX), which, respectively, generate nitric oxide (NO·) and superoxide (O2·−).
Sanjay Premi
doaj   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

open access: yesAdvanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong   +11 more
wiley   +1 more source

Neuroprotective effects of melanins and melanin derivatives from Calvatia Craniiformis and Xylaria plebeja against Parkinsonian toxins

open access: yesScientific Reports
Fungal melanins have remarkable bioactivities, but their practical applications are limited, partly due to their hydrophobic nature. Melanin modification with amino acids was reported to improve their water solubility. This research aimed to extract, and
Duong Thuy Nguyen   +5 more
doaj   +1 more source

Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs

open access: yesPharmaceutics, 2020
Interactions between drugs and melanin pigment may have major impacts on pharmacokinetics. Therefore, melanin binding can modify the efficacy and toxicity of medications in ophthalmic and other disease of pigmented tissues, such as melanoma.
Laura Hellinen   +5 more
doaj   +1 more source

Boron Nitride Reinforced Supramolecular Gels Nano‐Assembled with Fungicides toward Soil‐Borne Fungal Disease Management

open access: yesAdvanced Science, EarlyView.
This work demonstrates of 2D material‐mediated stimuli‐responsive transport in soft matter systems, pioneers a new class of nano‐bridged carriers with mechanically strengthening and programmable permeability characteristics designed to overcome persistent barriers in soil‐borne disease management.
Li Hao   +9 more
wiley   +1 more source

Multifunctional Gelatin‐Based Smart Films Integrating Thermochromic Encryption, Temperature‐Regulated Photothermal Management, Reprocessability, and Biodegradability for Sustainable Applications

open access: yesAdvanced Science, EarlyView.
Multifunctional gelatin films synergizing thermochromic encryption, self‐regulating photothermal management, and closed‐loop recyclability offer sustainable solutions for intelligent packaging. ABSTRACT Multifunctional gelatin‐based smart films are engineered by incorporating hyperbranched polyglycerol (HBPG) as a plasticizer, dialdehyde β‐cyclodextrin
Yuehong Zhang   +4 more
wiley   +1 more source

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