Results 21 to 30 of about 8,666 (209)

Glyphosate inhibits melanization and increases susceptibility to infection in insects

PLoS Biology, 2021
Melanin, a black-brown pigment found throughout all kingdoms of life, has diverse biological functions including UV protection, thermoregulation, oxidant scavenging, arthropod immunity, and microbial virulence.
Daniel F. Q. Smith, E. Camacho, Raviraj Thakur, Alexander J. Barron, Yuemei Dong, G. Dimopoulos, N. Broderick, A. Casadevall   +7 more
semanticscholar   +1 more source

Prophenoloxidase of Odontotermes formosanus (Shiraki) (Blattodea: Termitidae) Is a Key Gene in Melanization and Has a Defensive Role during Bacterial Infection

International Journal of Molecular Sciences, 2022
Melanization mediated by the prophenoloxidase (PPO)-activating system is an important innate immunity to fight pathogens in insects. In this study, the in vitro time-dependent increase in the intensity of melanization and phenoloxidase (PO) activity from
Zhiqiang Wang, Jian-Xin Luo, K. Feng, Yujingyun Zhou, F. Tang   +4 more
semanticscholar   +1 more source

Effect of Melanization on Thallus Microstructure in the Lichen Lobaria pulmonaria

Journal of Fungi, 2022
Lichens often grow in microhabitats where they experience severe abiotic stresses. Some species respond to high UV radiation by synthesizing dark brown melanic pigments in the upper cortex. However, unlike the melanized structures of non-lichenized fungi,
Amina G Daminova, A. Rogov, A. Rassabina, R. Beckett, F. Minibayeva   +4 more
semanticscholar   +1 more source

CLIPB10 is a Terminal Protease in the Regulatory Network That Controls Melanization in the African Malaria Mosquito Anopheles gambiae

Frontiers in Cellular and Infection Microbiology, 2021
Humoral immune responses in animals are often tightly controlled by regulated proteolysis. This proteolysis is exerted by extracellular protease cascades, whose activation culminates in the proteolytic cleavage of key immune proteins and enzymes. A model
Xin Zhang, Miao Li, Layla El Moussawi, S. Saab, Shasha Zhang, M. Osta, K. Michel   +6 more
semanticscholar   +1 more source

Melanization as unfavorable factor in amelanotic melanoma cell biology

Protoplasma, 2021
The biology of three amelanotic melanoma cell lines (Ab, B16F10, and A375) of different species origin was analyzed during in vitro induced melanization in these cells.
A. Skoniecka, M. Cichorek, A. Tymińska, I. Pelikant-Małecka, J. Dziewiątkowski   +4 more
semanticscholar   +1 more source

A phytoplasma effector suppresses insect melanization immune response to promote pathogen persistent transmission. [PDF]

Sci Adv
Insect melanization triggered by the conversion of prophenoloxidase to active phenoloxidase via serine proteases (SPs) is an important immediate immune response.
Zhang XF, Li Z, Qiu J, Zhang R, Jiang Z, Wang T, Chen H, Wei T.   +7 more
europepmc   +2 more sources

Activation of the Host Immune Response in Hyphantria cunea (Drury) (Lepidoptera: Noctuidae) Induced by Serratia marcescens Bizio

Insects, 2021
Host–pathogen interactions are essential to our understanding of biological pesticides. Hyphantria cunea (Drury) is an important forest pest worldwide. The immune mechanism of the interaction between H.
Zhiqiang Wang, Kai Feng, Fang Tang, Meng Xu   +3 more
doaj   +1 more source

Two clip-domain serine protease homologs, cSPH35 and cSPH242, act as a cofactor for prophenoloxidase-1 activation in Drosophila melanogaster

Frontiers in Immunology, 2023
Insect phenoloxidases (POs) catalyze phenol oxygenation and o-diphenol oxidation to form reactive intermediates that kill invading pathogens and form melanin polymers.
Qiao Jin, Yang Wang, Haodong Yin, Haobo Jiang   +3 more
doaj   +1 more source

Protein Kinase A Controls the Melanization of Candida auris through the Alteration of Cell Wall Components

Antioxidants, 2023
Candida auris, a multidrug-resistant fungal pathogen, significantly threatens global public health. Recent studies have identified melanin production, a key virulence factor in many pathogenic fungi that protects against external threats like reactive ...
Ji-Seok Kim, Yong-Sun Bahn
doaj   +1 more source

Antarctolichenia onofrii gen. nov. sp. nov. from Antarctic Endolithic Communities Untangles the Evolution of Rock-Inhabiting and Lichenized Fungi in Arthoniomycetes

Journal of Fungi, 2021
Microbial endolithic communities are the main and most widespread life forms in the coldest and hyper-arid desert of the McMurdo Dry Valleys and other ice-free areas across Victoria Land, Antarctica.
Lucia Muggia, Claudia Coleine, Roberto De Carolis, Agnese Cometto, Laura Selbmann   +4 more
doaj   +1 more source