Results 41 to 50 of about 1,543 (156)
Alpha-Melanocyte-Stimulating Hormone Maintains Retinal Homeostasis after Ischemia/Reperfusion
BiomoleculesAugmenting the natural melanocortin pathway in mouse eyes with uveitis or diabetes protects the retinas from degeneration. The retinal cells are protected from oxidative and apoptotic signals of death.
Tat Fong Ng +10 more
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Hypothalamic Melanocortin System on Feeding Regulation in Birds: A Review
The Journal of Poultry Science, 2011 Regulation of feed intake in chickens represents a complex homeostatic mechanism involving multiple levels of control. Understanding the regulation of feeding behavior can be a very important theme in animal production.
Takashi Bungo +2 more
doaj +1 more source
[Nle4, D-Phe7]-α-MSH Inhibits Toll-Like Receptor (TLR)2- and TLR4-Induced Microglial Activation and Promotes a M2-Like Phenotype. [PDF]
PLoS ONE, 2016 α-melanocyte stimulating hormone (α-MSH) is an anti-inflammatory peptide, proved to be beneficial in many neuroinflammatory disorders acting through melanocortin receptor 4 (MC4R).
Lila Carniglia +5 more
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The blue lizard spandrel and the island syndrome
BMC Evolutionary Biology, 2010 Background Many small vertebrates on islands grow larger, mature later, lay smaller clutches/litters, and are less sexually dimorphic and aggressive than their mainland relatives. This set of observations is referred to as the 'Island Syndrome'.
Monti Daria M +8 more
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Melanocortin Pathways: Suppressed and Stimulated Melanocortin-4 Receptor (MC4R)
Physiological Research, 2020 Leptin-melanocortin pathway plays an essential role in the body weight regulation. Enhanced melanocortin signaling in the hypothalamus results in both decreased food intake and increased energy expenditure. The discovery of monogenic obesities with dysfunction of melanocortin-4 receptor (MC4R) greatly contributed to understanding of energy balance ...
V, Hainer +5 more
openaire +2 more sources
American Journal of Ophthalmology Case Reports, 2016 Purpose: To describe the clinical course of a patient with non-infectious idiopathic unilateral panuveitis and retinal vasculitis treated with subcutaneous repository adrenocorticotropic hormone (ACTH) gel. Observations: A 33-year-old male presented with
Aniruddha Agarwal +4 more
doaj +1 more source
Novel α-MSH peptide analogues with broad spectrum antimicrobial activity.
PLoS ONE, 2013 Previous investigations indicate that α-melanocyte-stimulating hormone (α-MSH) and certain synthetic analogues of it exert antimicrobial effects against bacteria and yeasts.
Paolo Grieco +13 more
doaj +1 more source
Melanocortins and opiate addiction
Life Sciences, 1997 Adrenocorticotropic hormone (ACTH) and alpha-melanocyte stimulating hormone (alpha-MSH) are centrally acting melanocortin peptides with numerous reported functions, including induction of excessive grooming and antipyresis, among others. Also reported is a role for melanocortins in aspects of opiate action.
J D, Alvaro, J B, Tatro, R S, Duman
openaire +2 more sources
Molecular MetabolismHypothalamic neurons expressing either POMC or AGRP sense nutritional state directly and indirectly and transmit these neuropeptide signals to other brain centres through the melanocortin 3 and 4 receptors. MC4R is primarily concerned with the control of
Katie Duckett +24 more
doaj +1 more source
Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides
International Journal of Inflammation, 2013 The resolution of inflammation is now known to be an active process, armed with a multitude of mediators both lipid and protein in nature. Melanocortins are peptides endowed with considerable promise with their proresolution and anti-inflammatory effects
Tazeen J. Ahmed +3 more
doaj +1 more source