Role of the Melanocortin System in Gonadal Steroidogenesis of Zebrafish
Animals, 2022 In teleost, as in other vertebrates, stress affects reproduction. A key component of the stress response is the pituitary secretion of the adrenocorticotropic hormone (ACTH), which binds to the melanocortin 2 receptor (MC2R) in the adrenal glands and ...
Sandra Navarro +6 more
doaj +1 more source
The Melanocortin System in Control of Inflammation
The Scientific World Journal, 2010 Melanocortin peptides, the collective term for α-, β-, and γ-melanocyte-stimulating hormone (α-, β-, γ-MSH) and adrenocorticotropic hormone (ACTH), are elements of an ancient modulatory system.
Anna Catania +5 more
doaj +1 more source
Bird Integumentary Melanins: Biosynthesis, Forms, Function and Evolution [PDF]
, 2016 Melanins are the ubiquitous pigments distributed in nature. They are one of the main pigments responsible for colors in living cells. Birds are among the most diverse animals regarding melanin-based coloration, especially in the plumage, although they ...
Agrup +40 more
core +5 more sources
Central melanocortins regulate the motivation for sucrose reward. [PDF]
PLoS ONE, 2015 The role of the melanocortin (MC) system in feeding behavior is well established. Food intake is potently suppressed by central infusion of the MC 3/4 receptor agonist α-melanocyte stimulating hormone (α-MSH), whereas the MC 3/4 receptor inverse-agonist ...
Rahul Pandit +8 more
doaj +1 more source
Melanocortin receptors as novel effectors of macrophage responses in inflammation
Frontiers in Immunology, 2011 Macrophages have crucial functions in initiating the inflammatory reaction in a strict temporal and spatial manner to provide a ‘clear-up’ response required for resolution.
Hetal B Patel +3 more
doaj +1 more source
Glucocorticoid and Melanocortins: Special Issue [PDF]
The Scientific World Journal, 2007 Stephen J. Getting
doaj +3 more sources
Islet-1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood [PDF]
, 2015 Food intake and body weight regulation depend on proper expression of the proopiomelanocortin gene (Pomc) in a group of neurons located in the mediobasal hypothalamus of all vertebrates.
Gonzalez, Laura Elisabeth +6 more
core +2 more sources
Activation of melanocortin receptors MC1 and MC5 attenuates retinal damage in experimental diabetic retinopathy [PDF]
, 2016 We hypothesize that melanocortin receptors (MC) could activate tissue protective circuit in a model of streptozotocin- (STZ-) induced diabetic retinopathy (DR) in mice.
D'Amico, M. +29 more
core +4 more sources
Novel therapeutics in rare genetic obesities: A narrative review
Pharmacological Research, 2023 The better understanding of the molecular causes of rare genetic obesities and its associated phenotype involving the hypothalamus allows today to consider innovative therapeutics focused on hunger control.
Beatrice Dubern +3 more
doaj +1 more source
Physiopathological Implications of 7TM Receptors [PDF]
, 2010 Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core +2 more sources