Results 11 to 20 of about 1,543 (156)
Melanocortins, Melanocortin Receptors and Multiple Sclerosis
Brain Sciences, 2017 The melanocortins and their receptors have been extensively investigated for their roles in the hypothalamo-pituitary-adrenal axis, but to a lesser extent in immune cells and in the nervous system outside the hypothalamic axis.
Joyce Benjamins +2 more
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Developments and new vistas in the field of melanocortins
Biomolecular Concepts, 2015 Melanocortins play a fundamental role in several basic functions of the organism (sexual activity, feeding, inflammation and immune responses, pain sensitivity, response to stressful situations, motivation, attention, learning, and memory).
Sheila Leone, Alfio Bertolini
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Melanocortin Regulation of Inflammation [PDF]
Frontiers in Endocrinology, 2019 Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin receptors), are components of an ancient modulatory system.
Wei Wang +3 more
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The Melanocortin System in Control of Inflammation [PDF]
The Scientific World Journal, 2010 Melanocortin peptides, the collective term for α-, β-, and γ-melanocyte-stimulating hormone (α-, β-, γ-MSH) and adrenocorticotropic hormone (ACTH), are elements of an ancient modulatory system.
Anna Catania +5 more
doaj +4 more sources
Loss-of-function mutations in the melanocortin-2-receptor (mc2r) lead to skin hyperpigmentation in teleost fish [PDF]
Scientific ReportsMelanocortins regulate pigmentation via melanocortin receptors (MCRs), which are highly conserved across vertebrates. Unlike other MCRs, the melanocortin 2 receptor (MC2R) is exclusively activated by ACTH; however, its role in pigmentation remains ...
Elisa Barreiro-Docío +9 more
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Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins
Scientific World Journal, The, 2006 The natural antimicrobial peptides are ancient host defense effector molecules, present in organisms across the evolutionary spectrum. Several properties of α-melanocyte stimulating hormone (α-MSH) suggested that it could be a natural antimicrobial ...
Caterina Lonati +2 more
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International Journal of DiabetologyDiabetes mellitus (type I and II) is an advancing global health problem, concerningly increasing in prevalence in most of the developed and developing world.
Raelene Pickering
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Melanocortins and feeding behavior
Biomedicine and Pharmacotherapy, 2000 The melanocortin (ACTH/MSH) peptides exert a number of central effects. In the eighties, we described for the first time a role for melanocortins in the central control of appetite. We showed that the injection of ACTH-(1-24) into a brain lateral ventricle reduced food intake up to 76.6% in starved rats.
Helgi Schioth, Anna Valeria Vergoni
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Editorial: Melanocortins and melanocortin receptors in the regulation of inflammation: mechanisms and novel therapeutic strategies [PDF]
Frontiers in Immunology, 2023 Petteri Rinne +3 more
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The genetics of obesity: A narrative review [PDF]
Precision and Future Medicine, 2022 Monogenic obesity is a rare, early-onset, and severe form of obesity that has a Mendelian inheritance pattern, high penetrance, and large genetic effect. In contrast, common polygenic obesity is more prevalent and has pattern of heritability derived from
Young Bae Sohn
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