Results 11 to 20 of about 3,506 (222)
Melanocortin Regulation of Inflammation [PDF]
Frontiers in Endocrinology, 2019 Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin receptors), are components of an ancient modulatory system.
Wei Wang +3 more
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MOLECULAR EVOLUTION OF GPCRS: Melanocortin/melanocortin receptors [PDF]
Journal of Molecular Endocrinology, 2014 The melanocortin receptors (MCRs) are a family of G protein-coupled receptors that are activated by melanocortin ligands derived from the proprotein, proopiomelanocortin (POMC). During the radiation of the gnathostomes, the five receptors have become functionally segregated (i.e.
Robert M, Dores +5 more
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The effect of six weeks high intensity interval training on protein expression of Melanocortin 1 Receptor of monocytes and plasma levels of Alpha melanocyte stimulating hormone in overweight men [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2012 Objectives: The purpose of this study is to investigate the effect of six weeks high intensity interval training (HIT)on protein expression of Melanocortin 1 Receptor (MC1R) of monocytes and plasma levels of melanocytestimulating hormone alpha (∝-MSH) in
سید محسن آوندی +3 more
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From obesity resistance to obesity prediction and prevention? [PDF]
, 2016 Comment on: Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?
Cassano, Tommaso, Gaetani, Silvana
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Fish melanocortin system [PDF]
European Journal of Pharmacology, 2011 Melanocortin signalling is mediated by binding to a family of G protein-coupled receptors that positively couple to adenylyl cyclase. Tetrapod species have five melanocortin (MC(1)-MC(5)) receptors. The number of receptors varies in fish, zebrafish, for example, having six melanocortin receptors, with two copies of the melanocortin MC(5) receptor ...
Cerdá-Reverter, José Miguel +5 more
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Antifibrotic and Anti-Inflammatory Actions of α-Melanocytic Hormone: New Roles for an Old Player
Pharmaceuticals, 2021 The melanocortin system encompasses melanocortin peptides, five receptors, and two endogenous antagonists. Besides pigmentary effects generated by α-Melanocytic Hormone (α-MSH), new physiologic roles in sexual activity, exocrine secretion, energy ...
Roshan Dinparastisaleh, Mehdi Mirsaeidi
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The Multifaceted Melanocortin Receptors
Endocrinology, 2022 AbstractThe 5 known melanocortin receptors (MCs) have established physiological roles. With the exception of MC2, these receptors can behave unpredictably, and since they are more widely expressed than their established roles would suggest, it is likely that they have other poorly characterized functions.
Linda Laiho, Joanne Fiona Murray
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Novel Emerging Therapies for Erectile Dysfunction
The World Journal of Men's Health, 2021 Currently, several treatments exist for the improvement of erectile dysfunction (ED). These include medical therapies such as phosphodiesterase type 5 inhibitors (PDE5-Is), invasive methods such as intracavernosal injection therapy of vaso-active ...
Soyeun Kim +4 more
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Disruption of type 3 adenylyl cyclase expression in the hypothalamus leads to obesity [PDF]
, 2016 Evidence from human studies and transgenic mice lacking the type 3 adenylyl cyclase (AC3) indicates that AC3 plays a role in the regulation of body weight. It is unknown in which brain region AC3 exerts such an effect.
Cao, Hong +3 more
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Astrocytes: New Targets of Melanocortin 4 Receptor Actions [PDF]
, 2013 Astrocytes exert a wide variety of functions with paramount importance in brain physiology. After injury or infection, astrocytes become reactive and they respond by producing a variety of inflammatory mediators that help maintain brain homeostasis. Loss
Carniglia, Lila +4 more
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