Results 71 to 80 of about 3,506 (222)
ACTH Prevents Deficits in Fear Extinction Associated with Early Life Seizures
Frontiers in Neurology, 2016 Early life seizures are often associated with cognitive and psychiatric comorbidities that are detrimental to quality of life. In a rat model of early life seizures (ELS), we explored long-term cognitive outcomes in adult rats. Using ACTH, an endogeneous
Andrew T Massey +6 more
doaj +1 more source
Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. [PDF]
PLoS ONE, 2015 In this study, we showed that adrenocorticotropic hormone (ACTH) promoted erythroblast differentiation and increased the enucleation ratio of erythroblasts.
Eriko Simamura +9 more
doaj +1 more source
Addiction, EarlyView.Abstract Background and aims Addiction‐related behaviors, such as loss of control eating (LOC), cigarette smoking and alcohol consumption, have been associated with high body mass index (BMI). This study aimed to assess genetic and environmental contributions to these associations over time.
Baiyu Qi +10 more
wiley +1 more source
To Bet, or Not to Bet: That Is the Question of SEF Spikes [PDF]
, 2012 The ability of animals to monitor their own cognitive processes is called metacognition. In this issue of Neuron, Middlebrooks and Sommer (2012) show that single-unit activity of SEF neurons exhibit a metacognitive signal while monkeys perform a ...
Miyamoto, Kentaro +2 more
core +8 more sources
Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi +20 more
wiley +1 more source
Journal of Small Animal Practice, EarlyView.This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley +1 more source
Sex-specific phenotypic integration: Endocrine profiles, coloration, and behavior in fledgling boobies [PDF]
, 2015 The intensity of color expression in animals plays a key role in social environments as a mechanism to signal individual capacities in competitive contests. Selective pressures for resource competition differ at different stages of life and between sexes;
Fargallo, Juan A. +6 more
core +1 more source
Setmelanotide in Bardet‐Biedl Syndrome: A Case Report
Pediatric Dermatology, EarlyView.ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith +2 more
wiley +1 more source
Hypothalamic Melanocortin System on Feeding Regulation in Birds: A Review
The Journal of Poultry Science, 2011 Regulation of feed intake in chickens represents a complex homeostatic mechanism involving multiple levels of control. Understanding the regulation of feeding behavior can be a very important theme in animal production.
Takashi Bungo +2 more
doaj +1 more source
[Nle4, D-Phe7]-α-MSH Inhibits Toll-Like Receptor (TLR)2- and TLR4-Induced Microglial Activation and Promotes a M2-Like Phenotype. [PDF]
PLoS ONE, 2016 α-melanocyte stimulating hormone (α-MSH) is an anti-inflammatory peptide, proved to be beneficial in many neuroinflammatory disorders acting through melanocortin receptor 4 (MC4R).
Lila Carniglia +5 more
doaj +1 more source