Results 91 to 100 of about 184,486 (257)

Stress alters hypothalamic gene expression in adolescent male Golden hamsters

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract In Golden hamsters (Mesocricetus auratus), a two‐week exposure to chronic social stress in adolescence causes acceleration of agonistic behavior, enhanced adult aggression, impaired waiting impulsivity, and higher food intake, body fat, and long‐term increased body weight.
Kevin M. Moran   +3 more
wiley   +1 more source

Schmidt's Syndrome: An Uncommon Cause of Spontaneous Hypoglycemia

open access: yesAvicenna Journal of Medicine
Schmidt's syndrome, or autoimmune polyendocrine syndrome type 2 (APS-2), is an uncommon disorder characterized by the co-occurrence of autoimmune thyroiditis and adrenalitis.
George Sarin Zacharia   +2 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Regulation of melanocyte stimulating hormone action at the receptor level: discontinuous binding of hormone to synchronized mouse melanoma cells during the cell cycle.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1974
Melanocyte stimulating hormone coupled to Sepharose effects an increase in tryosinase (EC 1.14.18.1; monophenol monoxygenase) activity of cultivated mouse melanoma cells.
J. Varga   +4 more
semanticscholar   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin   +6 more
wiley   +1 more source

Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend PANX1 and PANX3 show opposite expression patterns in patient‐derived normal skin and cutaneous squamous cell carcinoma (cSCC) tumours, with PANX1 increased and PANX3 mRNA decreased in cSCC tumours compared to skin. Within the tumour PANX1 localizes to all regions, including tumour nests which house cSCC cancer cells and tumour ...
Brooke L. O'Donnell   +11 more
wiley   +1 more source

Quantum Chemical, Spectroscopic and In Silico (Molecular Docking, Molecular Dynamic and ADME) Studies on Anti‐Aging Pentapeptide‐3 (Vialox)

open access: yesInternational Journal of Quantum Chemistry, Volume 125, Issue 15, August 5, 2025.
This study investigates the anti‐aging potential of Pentapeptide‐3 (Vialox) using quantum chemical, spectroscopic, and in silico methods. Molecular docking and dynamics analysis confirm its stable interactions with key aging‐related receptors, highlighting Pentapeptide‐3 as a promising candidate for cosmeceutical applications targeting skin aging ...
Dilan Akhan   +3 more
wiley   +1 more source

Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies

open access: yesMedComm, Volume 6, Issue 8, August 2025.
Mechanisms of alleviating resistance to PD‐1/PD‐L1 blockade by IFN‐α and IFN‐β. In these mechanisms, the “yin‐yang balance” is disrupted, thus preventing T cells from attacking cancer cells. Restoring this balance may improve the efficacy of anti‐PD‐1/PD‐L1 therapy and reinvigorate T cells and other immune cells to target and destroy cancer cells ...
Peng Gao   +7 more
wiley   +1 more source

α-Melanocyte-stimulating hormone directly increases the plasma calcitonin level and involves calcium metabolism in goldfish

open access: yesInternational Aquatic Research, 2018
The effects of α-melanocyte-stimulating hormone (α-MSH) on calcium metabolism were examined with goldfish. The scales on the left side of goldfish bodies were removed to allow the regeneration of scales under anesthesia.
Takahiro Ikari   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy