Results 11 to 20 of about 190,071 (238)

α-Melanocyte-Stimulating Hormone Protects Retinal Vascular Endothelial Cells from Oxidative Stress and Apoptosis in a Rat Model of Diabetes

PLoS ONE, 2014
Aims Oxidative stress and apoptosis are among the earliest lesions of diabetic retinopathy. This study sought to examine the anti-oxidative and anti-apoptotic effects of α-melanocyte-stimulating hormone (α-MSH) in early diabetic retinas and to explore ...
Lijuan Zhang, Lijie Dong, Xun Liu, Yuanfeng Jiang, Lingjun Zhang, Xiaomin Zhang, Xiaorong Li, Yan Zhang   +7 more
openalex   +3 more sources

Anti-inflammatory treatment using alpha melanocyte stimulating hormone (α-MSH) does not alter osteoblasts differentiation and fracture healing. [PDF]

BMC Musculoskelet Disord
Background Alpha-melanocyte-stimulating-hormone (α-MSH) has been identified as a new anti-inflammatory treatment compound in rheumatoid arthritis (RA) and other inflammatory diseases.
Graue J, Timmen M, Schmitz K, Kronenberg D, Böhm M, Sivaraj KK, Bixel MG, Stange R.   +7 more
europepmc   +2 more sources

7,3',4'-Trihydroxyisoflavone, a Metabolite of the Soy Isoflavone Daidzein, Suppresses α-Melanocyte-Stimulating Hormone-Induced Melanogenesis by Targeting Melanocortin 1 Receptor. [PDF]

Front Mol Biosci, 2020
Kim JH, Lee JE, Kim T, Yeom MH, Park JS, di Luccio E, Chen H, Dong Z, Lee KW, Kang NJ.   +9 more
europepmc   +3 more sources

The Effect of Geographic Location, Breed, and Pituitary Dysfunction on Seasonal Adrenocorticotropin and α‐Melanocyte‐Stimulating Hormone Plasma Concentrations in Horses [PDF]

Journal of Veterinary Internal Medicine, 2011
Dianne McFarlane, Mary Rose Paradis, Dana N. Zimmel, B. W. Sykes, B. Wade Brorsen, A. Sánchez, Kirsti Vainio   +6 more
openalex   +2 more sources

Alpha-Melanocyte-Stimulating Hormone-Mediated Appetite Regulation in the Central Nervous System

Neuroendocrinology, 2023
Understanding the complex action mechanism of appetite regulation peptides can significantly impact therapeutic options in the treatment of obesity and other metabolic diseases. Hypothalamic alpha-melanocyte-stimulating hormone (α-MSH) is an anorexigenic
Qiwen Wu, Jingmei Chen, Tingyu Hua, Jinyan Cai   +3 more
semanticscholar   +1 more source

The α‐melanocyte‐stimulating hormone/melanocortin‐1 receptor interaction: A driver of pleiotropic effects beyond pigmentation

Pigment Cell & Melanoma Research, 2021
Melanocortin‐1 Receptor (MC1R), when stimulated by alpha‐melanocyte‐stimulating hormone (α‐MSH), is a driver of eumelanogenesis. Brown/black eumelanin is an effective filter against ultraviolet radiation (UVR) and is a scavenger of free radicals. Several
C. Herraiz, Idoya Martínez-Vicente, V. Maresca   +2 more
semanticscholar   +1 more source

The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans. [PDF]

PLoS ONE, 2010
BACKGROUND: The neuropeptide alpha-melanocyte-stimulating hormone is well known as a mediator of skin pigmentation. More recently, it has been shown that alpha-melanocyte-stimulating hormone also plays pivotal roles in energy homeostasis, sexual function,
Karin Loser, Thomas Brzoska, Vinzenz Oji, Matteo Auriemma, Maik Voskort, Verena Kupas, Lars Klenner, Cornelius Mensing, Axel Hauschild, Stefan Beissert, Thomas A Luger   +10 more
doaj   +1 more source

The Role of Proopiomelanocortin and α-Melanocyte-Stimulating Hormone in the Metabolic Syndrome in Psychiatric Disorders: A Narrative Mini-Review. [PDF]

Front Psychiatry, 2019
Raue S, Wedekind D, Wiltfang J, Schmidt U.   +3 more
europepmc   +3 more sources

MicroRNA-141-3p and microRNA-200a-3p regulate α-melanocyte stimulating hormone-stimulated melanogenesis by directly targeting microphthalmia-associated transcription factor

Scientific Reports, 2020
In recent years, it has been reported that non-coding RNAs, especially microRNAs (miRNAs) and long non-coding RNAs, act as melanogenesis-regulating molecules in melanocytes. We found that the expression levels of miR-141-3p and miR-200a-3p were decreased
T. Itoh, Kanako Fukatani, Ayaka Nakashima, Kengo Suzuki   +3 more
semanticscholar   +1 more source

Literature-Based Discovery to Elucidate the Biological Links between Resistant Hypertension and COVID-19

Biology, 2023
Multiple studies have reported new or exacerbated persistent or resistant hypertension in patients previously infected with COVID-19. We used literature-based discovery to identify and prioritize multi-scalar explanatory biology that relates resistant ...
David Kartchner, Kevin McCoy, Janhvi Dubey, Dongyu Zhang, Kevin Zheng, Rushda Umrani, James J. Kim, Cassie S. Mitchell   +7 more
doaj   +1 more source