Journal of Neuroscience, 2014 In Alzheimer's disease (AD), appropriate excitatory–inhibitory balance required for memory formation is impaired. Our objective was to elucidate deficits in the inhibitory GABAergic system in the TgCRND8 mouse model of AD to establish a link between ...
K. Ma, J. McLaurin
semanticscholar +1 more source
Preliminary study on MC1R polymorphism in some cattle breeds raised in Italy
Italian Journal of Animal Science, 2011 Most of the Western European cattle breeds consist of standardised breeds with a definite coat colour (Renieri et al., 1984). Thus coat colour could be useful to detect genetic markers for cattle breed identification.
C. Renieri +5 more
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Degradation of α-melanocyte-stimulating hormone photosensitized by pterin.
Organic and biomolecular chemistry, 2014 Oxidized pterins, efficient photosensitizers under UV-A irradiation, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder.
C. Castaño +4 more
semanticscholar +1 more source
Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma
Journal of Skin Cancer, 2011 Basal cell carcinoma (BCC) is the most common neoplasm in the Caucasian population. Only a fraction of BCC exhibits pigmentation. Lack of melanocyte colonization has been suggested to be due to p53-inactivating mutations in the BCC cells interfering with
Lídia M. Frey +2 more
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Treatment Strategies for Hypopigmentation in the Context of Burn Hypertrophic Scars
Plastic and Reconstructive Surgery, Global Open, 2018 Dyspigmentation in burn scars can contribute to the development of psychosocial complications after injury and can be detrimental to social reintegration and quality of life for burn survivors.
Bonnie C. Carney, BS +3 more
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Deoxyvasicinone with Anti-Melanogenic Activity from Marine-Derived Streptomyces sp. CNQ-617
Marine Drugs, 2022 The tricyclic quinazoline alkaloid deoxyvasicinone (DOV, 1) was isolated from a marine-derived Streptomyces sp. CNQ-617, and its anti-melanogenic effects were investigated.
Se-eun Lee +6 more
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Inhibition of tyrosinase activity and melanine pigmentation by 2-hydroxytyrosol
Acta Pharmaceutica Sinica B, 2014 2-Hydroxytyrosol (2-HT), originally reported as a synthetic compound, was isolated for the first time as a fungal metabolite. 2-HT was found to inhibit mushroom tyrosinase with an IC50 value of 13.0 µmol/L.
Ryuji Uchida +2 more
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Melanocortin System in Kidney Homeostasis and Disease: Novel Therapeutic Opportunities
Frontiers in Physiology, 2021 Melanocortin peptides, melanocortin receptors, melanocortin receptor accessory proteins, and endogenous antagonists of melanocortin receptors are the key components constituting the melanocortin hormone system, one of the most complex and important ...
Mingyang Chang +4 more
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Recent advances in anterior pituitary hormones and metabolic-associated fatty liver disease
Frontiers in EndocrinologyThe classical theory of the pituitary–target gland axis suggests that the hormones secreted by the pituitary gland only regulate the synthesis and secretion of target gland hormones, while the target gland hormones act on the tissues of the body to ...
Changqing Liu +7 more
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Combination of alpha-melanocyte stimulating hormone with conventional antibiotics against methicillin resistant Staphylococcus aureus. [PDF]
PLoS ONE, 2013 Our previous studies revealed that alpha-melanocyte stimulating hormone (α-MSH) is strongly active against Staphylococcus aureus (S. aureus) including methicillin resistant S. aureus (MRSA).
Madhuri Singh +3 more
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