Results 61 to 70 of about 188,005 (273)

Anti–melanogenic properties of FBCC–EP850 derived from Carex pumila Thunb

open access: yesAsian Pacific Journal of Tropical Biomedicine
Objective: To elucidate the anti-melanogenic potential of Carex pumila Thunb. extract (FBCC-EP850). Methods: A collection of 180 plant extracts was tested for inhibition of mushroom tyrosinase activity using an in vitro assay.
Mirissa Hewage Dumindu Kavinda   +4 more
doaj   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Sebum Excretion and Melanocyte-Stimulating Hormone in Hypoadrenalism

open access: yesJournal of Investigative Dermatology, 1974
The sebum excretion rate (SER) was measured in 6 patients with Addison's disease and to patients with Cushing's disease treated by bilateral adrenalectomy, all of whom were taking appropriate replacement therapy. Plasma β MSH concentrations were measured by radioimmunoassay in β of the patients.
A.J. Thody   +4 more
openaire   +3 more sources

The natriuretic mechanism of Gamma-Melanocyte-Stimulating Hormone [PDF]

open access: yesPeptides, 2011
Gamma-Melanocyte Stimulating Hormone (Gamma-MSH) regulates sodium (Na(+)) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R). The mechanism of the natriuretic effect is proposed to involve binding of MC3-R either in the kidney to directly inhibit tubular Na(+) transport or in the brain to inhibit central neural ...
Madhumitha Rajagopal   +3 more
openaire   +2 more sources

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

Protection of cultured brain endothelial cells from cytokine-induced damage by α-melanocyte stimulating hormone [PDF]

open access: yesPeerJ, 2018
The blood–brain barrier (BBB), an interface between the systemic circulation and the nervous system, can be a target of cytokines in inflammatory conditions.
András Harazin   +8 more
doaj   +2 more sources

The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)

open access: yesBiology Open, 2021
One of the main functions of physiological color change is thermoregulation. This change occurs much more rapidly than morphological color change, but the underlying mechanism remains poorly understood.
Kun Guo   +5 more
doaj   +1 more source

PEARL: Protein Eluting Alginate with Recombinant Lactobacilli

open access: yesSmall, EarlyView.
Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri   +7 more
wiley   +1 more source

NEVIGRAV Study: A Case–Control Analysis on Changes in Melanocytic Nevi During Pregnancy

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Pregnancy can influence modifications and appearance of melanocytic nevi, but studies report inconsistent findings, often lacking standardized methods and comparison groups. This study evaluates dermoscopic changes in nevi and the development of new melanocytic lesions in pregnant women using full‐body photography and digital dermoscopy ...
Vincenzo Maione   +7 more
wiley   +1 more source

Data on melanin production in B16F1 melanoma cells in the presence of emu oil

open access: yesData in Brief, 2016
Here, we present data on the effects of emu oil, obtained from emu (Dromaius novaehollandiae) fat deposits, on melanogenesis in B16F1 murine melanoma cells.
Minoru Ito   +4 more
doaj   +1 more source

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