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Ligands for Melanocortin Receptors: Beyond Melanocyte-Stimulating Hormones and Adrenocorticotropin [PDF]

open access: yesBiomolecules, 2022
The discovery of melanocortins in 1916 has resulted in more than 100 years of research focused on these peptides. Extensive studies have elucidated well-established functions of melanocortins mediated by cell surface receptors, including MSHR (melanocyte-
Xiao-Chen Yuan, Ya-Xiong Tao
doaj   +2 more sources

Recent advances in anterior pituitary hormones and metabolic-associated fatty liver disease [PDF]

open access: yesFrontiers in Endocrinology
The classical theory of the pituitary–target gland axis suggests that the hormones secreted by the pituitary gland only regulate the synthesis and secretion of target gland hormones, while the target gland hormones act on the tissues of the body to ...
Changqing Liu   +7 more
doaj   +2 more sources

Inactivation of adrenocorticotropin, α- and Β-melanocyte-stimulating hormones, vasopressin, and pituitary fraction H by adipose tissue

open access: hybridJournal of Lipid Research, 1964
Rat adipose tissue homogenate contains a peptidase or group of peptidases which abolish the adipokinetic activity of ACTH, α-MSH, Β-MSH, vasopressin, and pituitary fraction H.
Daniel Rudman   +4 more
doaj   +2 more sources

Natriuretic Properties of Melanocyte-Stimulating Hormones

open access: bronzeJournal of Cardiovascular Pharmacology, 1993
Proopiomelanocortin (POMC) is a protein that contains the amino acid sequences of numerous peptide hormones, including the melanocyte-stimulating hormones (MSH). MSH peptides of alpha, beta, and gamma primary structure are present in plasma, and all exhibit natriuretic activity.
Jean‐Pierre Valentin   +2 more
openalex   +3 more sources

Neuroendocrine and Molecular Interactions in Eating Disorders [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2014
There are three basic pillars for the development of eating disorders: genetic predisposition, neuro-endocrine-molecular changes in the brain and metabolic response to it.
Selma Bozkurt Zincir
doaj   +1 more source

Serum levels of hormones regulating appetite in patients with cystic fibrosis − a single-center, cross-sectional study

open access: yesFrontiers in Endocrinology, 2022
Cystic fibrosis (CF), which is the most common inherited genetically determined disease caused by a mutation in the gene for the CF transmembrane conductance regulator protein. Pulmonary failure is the leading cause of death in this population, while the
Sabina Galiniak   +3 more
doaj   +1 more source

Topmouth culter melanocortin-3 receptor: regulation by two isoforms of melanocortin-2 receptor accessory protein 2

open access: yesEndocrine Connections, 2021
Melanocortin-3 receptor (MC3R) is a regulator of energy homeostasis, and interaction of MC3R and melanocortin-2 receptor accessory protein 2 (MRAP2) plays a critical role in MC3R signaling of mammals.
Ren-Lei Ji   +6 more
doaj   +1 more source

Licorice zinc suppresses melanogenesis via inhibiting the activation of P38MAPK and JNK signaling pathway in C57BL/6J mice skin

open access: yesActa Cirúrgica Brasileira, 2022
Purpose: The active melanocytes in the skin were affected by hormones and ultraviolet (UV) irradiation. Licorice zinc has a whitening effect, which may have a prominent potential in the treatment of pigmented skin disease.
Jing-yan Wang   +6 more
doaj   +1 more source

Keratinocytes regulate the function of melanocytes

open access: yesDermatologica Sinica, 2014
Mammalian keratinocytes compose the bulk of the epithelium, undergo keratinization, and form the dead superficial layer of the skin. These superficial keratinized cells are continuously replaced by cells derived from mitotic cells in the lowest layer of ...
Tomohisa Hirobe
doaj   +1 more source

Transgenerational Social Stress, Immune Factors, Hormones, and Social Behavior

open access: yesFrontiers in Ecology and Evolution, 2016
A social signal transduction theory of depression has been proposed that states that exposure to social adversity alters the immune response and these changes mediate symptoms of depression such as anhedonia and impairments in social behavior.
Christopher Anthony Murgatroyd   +5 more
doaj   +1 more source

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