Results 11 to 20 of about 6,975 (237)
Rab3a is critical for trapping alpha-MSH granules in the high Ca²⁺-affinity pool by preventing constitutive exocytosis. [PDF]
PLoS ONE, 2013 Rab3a is a small GTPase of the Rab3 subfamily that acts during late stages of Ca²⁺-regulated exocytosis. Previous functional analysis in pituitary melanotrophs described Rab3a as a positive regulator of Ca²⁺-dependent exocytosis.
Simon Sedej +3 more
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alpha-Melanocyte stimulating hormone: production and degradation [PDF]
Journal of Molecular Medicine, 2010 Proopiomelanocortin (POMC) is a polypeptide hormone precursor that is expressed in the brain and in peripheral tissues such as in the pituitary gland, immune system, and skin. In the brain, POMC is processed to form several peptides including alpha-melanocyte stimulating hormone (α-MSH). alpha-MSH is expressed in the hypothalamic arcuate nucleus and in
D'Agostino, Giuseppe, Diano, Sabrina
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FEBS Open Bio, 2021 Camellia japonica L. is a flowering tree with several medicinal and cosmetic applications. Here, we investigated the efficacy of C. japonica placenta extract (CJPE) as a potential therapeutic agent for promotion of hair growth and scalp health by using ...
Won Kyong Cho +12 more
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Life, 2023 In animal models, melanocyte-stimulating hormones (MSHs) protect the liver from various injuries. Erythropoietic protoporphyria (EPP), a metabolic disorder, leads to the accumulation of protoporphyrin (PPIX).
Anna-Elisabeth Minder +4 more
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Effects of Anterior Pituitary Adenomas’ Hormones on Glucose Metabolism and Its Clinical Implications
Diabetes, Metabolic Syndrome and Obesity, 2023 Mengnan Li,1,2 Jian Zhang,1,2 Guimei Yang,1,2 Jiaxin Zhang,1,2 Minmin Han,1,2 Yi Zhang,3 Yunfeng Liu1 1Department of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China; 2First Clinical Medical College, Shanxi ...
Li M +6 more
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Frontiers in Endocrinology, 2014 Nutrients created by the digestion of food are proposed to active G protein coupled receptors on the luminal side of enteroendocrine cells e.g. the L-cell. This stimulates the release of gut hormones.
Carmen Sobrino Crespo +5 more
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Melanocortin Regulation of Inflammation
Frontiers in Endocrinology, 2019 Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin receptors), are components of an ancient modulatory system.
Wei Wang +3 more
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Radioimmunoassay for Alpha Melanocyte Stimulating Hormone
Experimental Biology and Medicine, 1966 SummaryA radioimmunoassay has been developed for alpha melanocyte stimulating hormone (ae MSH). The assay compares favorably with biologic assays in terms of sensitivity and appears to be better in terms of precision and specificity.
T. Goodfriend, G. T. Ross, W. D. Odell
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The multiplicity of post-translational modifications in pro-opiomelanocortin-derived peptides
Frontiers in Endocrinology, 2013 The precursor protein, pro-opiomelanocortin (POMC) undergoes extensive post-translational processing in a tissue-specific manner to yield various biologically active peptides involved in diverse cellular functions.
Akikazu eYasuda +2 more
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Frontiers in Endocrinology, 2021 Proopiomelanocortin (POMC) deficiency is an extremely rare inherited autosomal recessive disorder characterized by severe obesity, adrenal insufficiency, skin hypopigmentation, and red hair. It is caused by pathogenic variants in the POMC gene that codes
Nadan Gregoric +18 more
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