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Natriuretic Properties of Melanocyte-Stimulating Hormones
Proopiomelanocortin (POMC) is a protein that contains the amino acid sequences of numerous peptide hormones, including the melanocyte-stimulating hormones (MSH). MSH peptides of alpha, beta, and gamma primary structure are present in plasma, and all exhibit natriuretic activity.
Jean-Pierre Valentin+2 more
semanticscholar +4 more sources
Ligands for Melanocortin Receptors: Beyond Melanocyte-Stimulating Hormones and Adrenocorticotropin [PDF]
The discovery of melanocortins in 1916 has resulted in more than 100 years of research focused on these peptides. Extensive studies have elucidated well-established functions of melanocortins mediated by cell surface receptors, including MSHR (melanocyte-
Xiao-Chen Yuan, Ya-Xiong Tao
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Recent advances in anterior pituitary hormones and metabolic-associated fatty liver disease [PDF]
The classical theory of the pituitary–target gland axis suggests that the hormones secreted by the pituitary gland only regulate the synthesis and secretion of target gland hormones, while the target gland hormones act on the tissues of the body to ...
Changqing Liu+7 more
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Plasma ACTH, α-MSH and cortisol variations in the dog during the oestrous cycle in different photoperiods [PDF]
The hypothalamic-pituitary-adrenal axis (HPA) is a complex system regulated by multiple factors. Sexual dimorphism of this axis has been described in different species under physiological conditions and it has been proposed that sexual hormones could ...
M.F. Gallelli+6 more
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Rat adipose tissue homogenate contains a peptidase or group of peptidases which abolish the adipokinetic activity of ACTH, α-MSH, Β-MSH, vasopressin, and pituitary fraction H.
Daniel Rudman+4 more
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Melanocortin Antagonists Define Two Distinct Pathways of Cardiovascular Control by α- and γ-Melanocyte-Stimulating Hormones [PDF]
Melanocortin peptides and at least two subtypes of melanocortin receptors (MC3-R and MC4-R) are present in brain regions involved in cardiovascular regulation.
Si-Jia Li+7 more
semanticscholar +2 more sources
Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective [PDF]
The melanocortin-4 receptor (MC4R) can be endogenously activated by binding of melanocyte-stimulating hormones (MSH), which mediates anorexigenic effects. In contrast, the agouti-related peptide (AgRP) acts as an endogenous inverse agonist and suppresses
Nicolas Heyder+10 more
doaj +3 more sources
It is now well established that GPR139, a G-protein coupled receptor exclusively expressed in the brain and pituitary, is activated by the essential amino acids L-tryptophan (L-Trp) and L-phenylalanine (L-Phe) via Gαq-coupling.
Diane Nepomuceno+5 more
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Studies on pituitary polypeptide hormones. I. The structure of beta-melanocyte-stimulating hormone from pig pituitary glands. [PDF]
J. Harris, P. Roos
semanticscholar +2 more sources