Results 71 to 80 of about 185,946 (280)

Sebum Excretion and Melanocyte-Stimulating Hormone in Hypoadrenalism

Journal of Investigative Dermatology, 1974
The sebum excretion rate (SER) was measured in 6 patients with Addison's disease and to patients with Cushing's disease treated by bilateral adrenalectomy, all of whom were taking appropriate replacement therapy. Plasma β MSH concentrations were measured by radioimmunoassay in β of the patients.
A.J. Thody, N. Plummer, S.K. Goolamali, Sam Shuster, J.L. Burton   +4 more
openaire   +3 more sources

The natriuretic mechanism of Gamma-Melanocyte-Stimulating Hormone [PDF]

Peptides, 2011
Gamma-Melanocyte Stimulating Hormone (Gamma-MSH) regulates sodium (Na(+)) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R). The mechanism of the natriuretic effect is proposed to involve binding of MC3-R either in the kidney to directly inhibit tubular Na(+) transport or in the brain to inhibit central neural ...
Madhumitha Rajagopal, Paru P. Kathpalia, Alan C. Pao, Carol Charlton   +3 more
openaire   +2 more sources

NEVIGRAV Study: A Case–Control Analysis on Changes in Melanocytic Nevi During Pregnancy

The Journal of Dermatology, EarlyView.
ABSTRACT Pregnancy can influence modifications and appearance of melanocytic nevi, but studies report inconsistent findings, often lacking standardized methods and comparison groups. This study evaluates dermoscopic changes in nevi and the development of new melanocytic lesions in pregnant women using full‐body photography and digital dermoscopy ...
Vincenzo Maione, Anna Venturuzzo, Stefano Bighetti, Carola Romanó, Zeno Fratton, Enzo Errichetti, Marina Venturini, Luca Bettolini   +7 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Anorexigenic Hormones Leptin, Insulin, and α-Melanocyte-Stimulating Hormone Directly Induce Neurotensin (NT) Gene Expression in Novel NT-Expressing Cell Models

Journal of Neuroscience, 2005
Neurotensin (NT) is implicated in the regulation of energy homeostasis, in addition to its many described physiological functions. NT is postulated to mediate, in part, the effects of leptin in the hypothalamus.
H. Cui, F. Cai, D. Belsham
semanticscholar   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Effects of the POMC System on Glucose Homeostasis and Potential Therapeutic Targets for Obesity and Diabetes

Diabetes, Metabolic Syndrome and Obesity, 2022
Dan Yang,1,2 Xintong Hou,1,2 Guimei Yang,1,2 Mengnan Li,1,2 Jian Zhang,1,2 Minmin Han,1,2 Yi Zhang,3 Yunfeng Liu1 1Department of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China; 2First Clinical Medical ...
Yang D, Hou X, Yang G, Li M, Zhang J, Han M, Zhang Y, Liu Y   +7 more
doaj  

Pigment-dispersing activities and cortisol-releasing activities of melanocortins and their receptors in xanthophores and head kidneys of the goldfish Carassius auratus [PDF]

, 2011
The five subtypes of melanocortin receptors (MCRs) mediate the functions of α-melanocyte-stimulating hormone (α-MSH) and adrenocorticotropic hormone (ACTH). In fish, these hormones are involved in pigment dispersion and cortisol release, respectively.
Cerdá-Reverter, José Miguel, Chiba, Hiroaki, Kobayashi, Yuki, Mizusawa, Kanta, Suzuki, Nobuo, Takahashi, Akiyoshi   +5 more
core   +2 more sources

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Gene transfer to chicks using lentiviral vectors administered via the embryonic chorioallantoic membrane.

PLoS ONE, 2012
The lack of affordable techniques for gene transfer in birds has inhibited the advancement of molecular studies in avian species. Here we demonstrate a new approach for introducing genes into chicken somatic tissues by administration of a lentiviral ...
Gideon Hen, Sara Yosefi, Dmitry Shinder, Adi Or, Sivan Mygdal, Reba Condiotti, Eithan Galun, Amir Bor, Dalit Sela-Donenfeld, Miriam Friedman-Einat   +9 more
doaj   +1 more source