Results 71 to 80 of about 6,975 (237)

The experimental generation of antibodies to alpha-melanocyte stimulating hormone and adrenocorticotropic hormone. [PDF]

, 1965
Joseph McGuire, R. McGill, Susan E. Leeman, Theodore L. Goodfriend   +3 more
openalex   +1 more source

Functional, Nutraceutical and Health Endorsing Perspectives of Saffron

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Saffron is generally regarded as safe for human consumption in moderate quantities, its potential adverse effects at higher doses require careful consideration. This review presents a balanced perspective on saffron's medicinal potential and its safe usage, making it a valuable resource for researchers and healthcare professionals.
Tabussam Tufail, Huma Badr ul Ain, Ali Ikram, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi   +4 more
wiley   +1 more source

Melanocyte-stimulating hormone—mimetic action of the phenothiazines

Journal of Pharmacy and Pharmacology, 1978
AbstractWe have compared the melanophore-stimulating action of four phenothiazines, trifluoperazine, perphenazine, chlorpromazine, and prochlorperazine, with α-MSH on the skin of the lizard Anolis carolinensis, using a new rate method of bioassay. The dose-response curves for the phenothiazines were parallel to that of α-MSH, and when given together α ...
Sam Shuster, R. J. Carter
openaire   +3 more sources

Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Eugenol (Eug), a volatile phenolic bioactive compound with formula of C10H12O2 have been reported with anticancer, antidiabetic, cardio‐ and pulmonary protective role. Moreover, it has the ability to improve gut health and prevent neurodegenerative disorders. According to WHO, the safe dose of Eug is 2.5 mg/kg for consumption.
Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Aimen Mazhar, Waqas Ahmad Khan, Muhammad Imran, Muzzamal Hussain, Ehab M. Mostafa, Ahmed H. El‐Ghorab, Mohammed M. Ghoneim, Samy Selim, Mohamed A. Abdelgawad, Entessar Al Jbawi, Suliman A. Alsagaby, Waleed Al Abdulmonem   +13 more
wiley   +1 more source

Ribosomal S6 kinase 2-forkhead box protein O4 signaling pathway plays an essential role in melanogenesis

Scientific Reports
Although previous studies have examined the signaling pathway involved in melanogenesis through which ultraviolet (UV) or α-melanocyte-stimulating hormones (α-MSH) stimuli act as key inducers to produce melanin at the stratum basal layer of the epidermis,
Dohyun Jeung, Ga-Eun Lee, Weidong Chen, Jiin Byun, Soo-Bin Nam, You-Min Park, Hye Suk Lee, Han Chang Kang, Joo Young Lee, Kwang Dong Kim, Young-Soo Hong, Cheol-Jung Lee, Dae Joon Kim, Yong-Yeon Cho   +13 more
doaj   +1 more source

Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies

MedComm, Volume 6, Issue 8, August 2025.
Mechanisms of alleviating resistance to PD‐1/PD‐L1 blockade by IFN‐α and IFN‐β. In these mechanisms, the “yin‐yang balance” is disrupted, thus preventing T cells from attacking cancer cells. Restoring this balance may improve the efficacy of anti‐PD‐1/PD‐L1 therapy and reinvigorate T cells and other immune cells to target and destroy cancer cells ...
Peng Gao, Xiao Li, Zhenyu Duan, Yang Wang, Yinggang Li, Jing Wang, Kui Luo, Jie Chen   +7 more
wiley   +1 more source

Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake

The FEBS Journal, Volume 292, Issue 15, Page 3900-3909, August 2025.
Estrogen is regulated by the rate‐limiting enzyme aromatase. This study examines how neuroestrogens, estrogen produced in the brain, regulate appetite through the hypothalamus. Using ovariectomized, aromatase knockout, and brain‐specific aromatase‐restored mice, the study found that neuroestrogens suppress appetite by influencing genes like Mc4r.
Takanori Hayashi, Kanako Kumamoto, Tatsuya Kobayashi, Xinfeng Hou, Shizuko Nagao, Nobuhiro Harada, Shinichiro Honda, Yohei Shimono, Eiji Nishio   +8 more
wiley   +1 more source

Aging of the Human Lip: Current Knowledge and Clinical Implications

Journal of Cosmetic Dermatology, Volume 24, Issue 8, August 2025.
ABSTRACT Background Comprehensive exploration of lip aging remains limited due to anatomical complexity of the structure, with current investigations predominantly focusing on aspects such as dryness management, cheilitis prevention and treatment, and surgical lifts.
Fanghui Sun, Yue Liu, Tao Zhang
wiley   +1 more source

Efficacy of Botulinum Toxin A for the Management of Melasma: A Split‐Face, Randomized Control Study

Journal of Cosmetic Dermatology, Volume 24, Issue 8, August 2025.
ABSTRACT Background Melasma management remains challenging due to its multifactorial nature pathogenesis and recurrent nature. Previous studies showed positive effects of botulinum toxin A (BoNT‐A) for treating and preventing ultraviolet‐induced hyperpigmentation.
Sasipim Chaijaras, Suphagan Boonpethkaew, Sonphet Chirasuthat, Nawara Sakpuwadol, Tanat Yongpisarn, Pimsiri Anansiripun, Vasanop Vachiramon   +6 more
wiley   +1 more source

Fractional and Non‐Fractional Picosecond Nd:YAG Lasers Combined With Fractional Picosecond KTP Laser for the Treatment of Melasma in Female Chinese

Skin Research and Technology, Volume 31, Issue 8, August 2025.
ABSTRACT Background and Objectives Melasma is a chronic pigmented lesion on the face that is challenging to treat. Single laser treatments are usually ineffective. Recently, picosecond lasers are becoming an emerging option for the treatment of melasma.
Changhan Chen, Youhui Ke
wiley   +1 more source