Results 121 to 130 of about 62,888 (340)
Diffuse Melanosis Cutis Under Immuno‐ and Targeted Therapy
JEADV Clinical Practice, EarlyView.ABSTRACT In patients with highly advanced melanoma, rarely a diffuse melanosis cutis (DMC) can be noticed. Even though the condition is generally harmless itself, it can have a significant impact on the patient's well‐being as an obvious mark of the disease. DMC causes a grey or brown discoloration of the skin and mucous membranes. We report on a young
Christiane Cussigh +3 more
wiley +1 more source
eLife, 2017 The neural crest is a dynamic progenitor cell population that arises at the border of neural and non-neural ectoderm. The inductive roles of FGF, Wnt, and BMP at the neural plate border are well established, but the signals required for subsequent neural
Christie Ciarlo +11 more
doaj +1 more source
Pilot Study of Tildrakizumab in the Treatment of Stable Non‐Segmental Vitiligo
JEADV Clinical Practice, EarlyView.ABSTRACT Background Treatment for vitiligo is limited, with variable efficacy, and can be time‐consuming or expensive. Recent developments within biologic therapy have demonstrated promising results with managing chronic autoimmune conditions. Objectives To evaluate the efficacy of tildrakizumab in inducing repigmentation in vitiligo.
Henry Lee +13 more
wiley +1 more source
The experimental generation of antibodies to alpha-melanocyte stimulating hormone and adrenocorticotropic hormone. [PDF]
, 1965 Joseph McGuire +3 more
openalex +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley +1 more source
Indian Dermatology Online Journal, 2014 Pigmentation featured millions of years ago and perhaps began with an amoeba frightening off a predator with some agent such as dopamine to prevent its attachment for phagocytosis by an enemy. This paper suggests that the environmental forces of grip and
Sanju Arianayagam, Terence J Ryan
doaj +1 more source
Med Research, EarlyView.ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin +8 more
wiley +1 more source
In vivo assay for melanocyte lightening substances [PDF]
, 1966 Abba J. Kastin, Andrew V. Schally
openalex +1 more source
The Journal of Pathology, EarlyView.Abstract Chondroitin sulfate proteoglycan 4 (CSPG4) is a promising target for melanoma immunotherapy, but its expression in benign melanocytic lesions and its diagnostic value remain unexplored. This study assessed CSPG4 expression in benign nevi (BN), dysplastic nevi (DN), and superficial spreading melanomas (SSM), comparing it with PRAME ...
Elias AT Koch +8 more
wiley +1 more source