Results 161 to 170 of about 78,152 (310)

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Well‐being in German patients with vitiligo in genital and visible areas – a pilot study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Only a few studies exist on the psychosocial impact of vitiligo in German patients, in particular those affected in genital and visible body areas. Methods This monocentric pilot study aimed to assess well‐being of adult patients with vitiligo and to compare sex, age, and clinical characteristics between patients with and without ...
Janne Ohlenbusch, Rachel Sommer, Kerstin Steinbrink, Markus Böhm   +3 more
wiley   +1 more source

Elevated expression of MITF counteracts B-RAF–stimulated melanocyte and melanoma cell proliferation

, 2005
Claudia Wellbrock, Richard Marais
openalex   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors

International Journal of Cosmetic Science, EarlyView.
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin, Béatrice Le Varlet, Claire Regazzetti, Thierry Passeron, Jinhua Wang, David E. Fisher, Philippe Schaison, Braham Shroot   +7 more
wiley   +1 more source

B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance [PDF]

, 2012
Agathe Valluet, Sabine Druillennec, Céline Barbotin, Coralie Dorard, Anne H. Monsoro‐Burq, Magalie Larcher, Célio Pouponnot, Manuela Baccarini, Lionel Larue, Alain Eychène   +9 more
openalex   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

International Journal of Cosmetic Science, EarlyView.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier, Morgane De Tollenaere, Cyrille Jarrin, Emilie Chapuis, Marine Bracq, Laura Lapierre, Catherine Zanchetta, Jean Tiguemounine, Amandine Scandolera, Romain Reynaud   +9 more
wiley   +1 more source

Rab27a Regulates the Peripheral Distribution of Melanosomes in Melanocytes [PDF]

, 2001
Alistair N. Hume, Lucy Collinson, Andrzej Rapak, Anita Quintal Gomes, Colin R. Hopkins, Miguel C. Seabra   +5 more
openalex   +1 more source

Deubiquitination of MITF-M regulates melanocytes proliferation and apoptosis

, 2021
Shuaishuai Hu
openalex   +1 more source

Bioretinoids from microalgae: Boosting retinol performance and tolerability

International Journal of Cosmetic Science, EarlyView.
A novel microalgae‐derived bioretinoid (MBR) enhances skin regeneration, improves pigmentation, and reduces signs of ageing more effectively than bakuchiol and comparably to retinol—without the irritation. MBR also synergizes with retinol, boosting hydration and safety. A powerful, gentle alternative for advanced skincare.
Silvia Sánchez‐Díez, Alexandre Lapeyre, Noemí García‐Delgado, Jordi Ayats   +3 more
wiley   +1 more source