Mast Cells in Host Defense Against Cutaneous Staphylococcus aureus Infection
Impact of S. aureus epicutaneous sensitization models on mast cell function in vivo. D. farinae and Staphylococcal enterotoxin B (SEB) activate Trpv1+ Tac1+ nociceptors to trigger the release of substance P (SP), which promotes mast cell degranulation through Mrgprb2. S.
Hannah Dychtenberg +3 more
wiley +1 more source
Consensus on energy‐based devices for keloids and hypertrophic scars: A Latin American Delphi study
Latin American Delphi consensus supports a sequential, multimodal approach to keloids and hypertrophic scars: vascular devices for early/inflammatory lesions; intralesional triamcinolone + 5‐fluorouracil and other injectable drugs for active scars; fractional lasers for texture; and pigment‐targeting therapies for dyschromia, prioritizing safety in ...
Gisele Viana de Oliveira +24 more
wiley +1 more source
Antimelanoma Activity of the Mastoparan Peptides MPX and MP1: Cellular Selectivity and Mechanism of Action. [PDF]
Sansone Semerdjian A, Arcisio-Miranda M.
europepmc +1 more source
Early systemic intervention for vitiligo: A prospective bicentric interventional study
Patients with non‐segmental vitiligo were enrolled into three groups according to the duration and activity of their disease. All subjects received NB‐UVB phototherapy and an oral mini‐pulse of systemic corticosteroids twice weekly for 6 months. Early systemic treatment allows better repigmentation, including in difficult‐to‐treat areas.
Clemence Bertold +8 more
wiley +1 more source
Establishment of Stable Immortalized Human Choroidal Melanocytes for Ocular Research. [PDF]
Fuentes-Rodriguez A +5 more
europepmc +1 more source
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer +9 more
wiley +1 more source
Downregulation of Lonp1 Promotes Melanocyte Pyroptosis via Suppressing Mitophagy and Activating NLRP3 Pathway in Vitiligo under Oxidative Stress. [PDF]
Huang X +9 more
europepmc +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Vitiligo as a Failure of Immune Resolution and Tissue Regeneration: From Stress Signals to Targeted Immune Modulation. [PDF]
Pupo Silvestrini AV +3 more
europepmc +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source

