International Dermoscopy Society consensus recommendations for the management of lentigo maligna
Lentigo maligna (LM) poses diagnostic and therapeutic challenges amid rising incidence and limited high‐quality evidence. This international expert consensus provides pragmatic, evidence‐based and expertise‐informed guidance on LM diagnosis and management.
Ana‐Maria Forsea +52 more
wiley +1 more source
Pathogenesis of Chemical Leukoderma and Chemical-Induced Vitiligo. [PDF]
Kuroda Y, Yang L, Katayama I.
europepmc +1 more source
OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta +4 more
wiley +1 more source
Germline inactivation of tumor suppressor BAP1 is associated with white spotting. [PDF]
Njauw CN +9 more
europepmc +1 more source
Dynamic colour change predicts movement behaviour in a diadromous fish
Abstract Dynamic changes in colour and pattern facilitate key behavioural functions in animals, particularly camouflage for predator avoidance. However, the benefits of colour change depend on the environmental and behavioural contexts. We tested how colour change interacts with movement behaviour in a freshwater fish by filming individuals in an open ...
Joshua S. Barrow, John R. Morrongiello
wiley +1 more source
Artificial Intelligence for Lentigo Maligna: Automated Margin Assessment via Sox-10-Based Melanocyte Density Mapping. [PDF]
Löper R +5 more
europepmc +1 more source
ABSTRACT The objective of this study was to evaluate welfare and health effects following single and repeated non‐lethal blood sampling from the caudal vasculature of Atlantic salmon. Two experiments were conducted at three different temperatures: a 6‐week freshwater experiment with fish weighing 50–100 g, undergoing up to four blood withdrawals, and a
Harriet Romstad +9 more
wiley +1 more source
Morphological and Optical Characterization of NRAS-Mutant Melanoma Cells and Primary Melanocytes via Quantitative Phase Imaging With Digital Holographic Microscopy. [PDF]
Farhat AA +3 more
europepmc +1 more source
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou +6 more
wiley +1 more source
Hair Graying as an Evolutionary Checkpoint against Malignancy: a Stem Cell Perspective. [PDF]
Şensoy Gün B.
europepmc +1 more source

