Results 261 to 270 of about 78,152 (310)

Deep learning finds convergent melanocytic morphology despite noisy archival slides. [PDF]

open access: yesCell Rep Methods
Tada M   +5 more
europepmc   +1 more source

Using an Unbiased Coexpression Network to Reveal Cross‐Talking Pathways of Phosphoinositide‐3‐Kinase Regulatory Subunit 1 in Skin Aging and Rejuvenation

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Mechanistic pathways of PIK3R1 in skin aging and rejuvenation were analyzed by bioinformatics approach and Gene Expression Omnibus database. Compared with young skin, PIK3R1 was differentially expressed in aged and IPL rejuvenated skin. Coexpression and network analyses revealed that PIK3R1 jointly participated in skin aging and rejuvenation via PI3K ...
Zhike Zhou   +8 more
wiley   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, Volume 600, Issue 1, Page 20-38, January 2026.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

The effect of oncometabolite 2-hydroxyglutarate on the biological behavior of differentiated melanocytes and uveal melanoma cells

open access: green, 2016
Cindy Weidmann   +6 more
openalex   +1 more source

Dacarbazine as a Positive Control in Melanoma Cell Lines (A375, SK‐MEL‐103, 1205Lu) and a Human Ex Vivo Skin Model

open access: yesAdvanced Biology, Volume 10, Issue 1, January 2026.
The work seeked to demonstrate the drug Dacarbazine as a positive control for toxicity tests in immortalized skin cells (keratinocytes and fibroblasts) and in different neoplastic cell lines, through the assay with resazurin. In addition, an alternative model to replace animals in experimental studies, using skin explant culture (hOSEC ‐ human ...
Marcel Nani Leite   +6 more
wiley   +1 more source

The Impact of Sleep Quality on Skin Color. [PDF]

open access: yesIndian Dermatol Online J
Xu J, Cai X, Qiao J, Qiao J, Fang H.
europepmc   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor   +12 more
wiley   +1 more source

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