Results 81 to 90 of about 76,131 (358)
YY1 regulates melanocyte development and function by cooperating with MITF. [PDF]
Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and
Juying Li+10 more
doaj +1 more source
SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma [PDF]
Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread.
Bellenghi, Maria+8 more
core +1 more source
Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli+6 more
wiley +1 more source
Keratinocytes regulate the function of melanocytes
Mammalian keratinocytes compose the bulk of the epithelium, undergo keratinization, and form the dead superficial layer of the skin. These superficial keratinized cells are continuously replaced by cells derived from mitotic cells in the lowest layer of ...
Tomohisa Hirobe
doaj +1 more source
Race Does Not Predict Melanocyte Heterogeneous Responses to Dermal Fibroblast-Derived Mediators. [PDF]
Abnormal pigmentation following cutaneous injury causes significant patient distress and represents a barrier to recovery. Wound depth and patient characteristics influence scar pigmentation.
Pornthep Sirimahachaiyakul+8 more
doaj +1 more source
CircRNAs have been reported to play essential roles in regulating immunity and inflammation, which may be an important regulatory factor in the development of vitiligo.
Lili Li+8 more
doaj +1 more source
Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
University Hospital, Evans Memorial Department of Clinical Research and Preventive Medicine
core
Transplantation of Human Melanocytes
Recent advances in the culturing of pigment cells from human beings have made it possible to begin the transplantation of autologous melanocytes into areas of skin that are hypopigmented. In a patient with piebaldism we were able to take pigment cells from a shave biopsy of the normally pigmented skin of the back, expand the cells in culture, and ...
Gisela Moellmann+3 more
openaire +3 more sources
Possibilities of Inner Ear Barrier Models for Otologic Drug Development
This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn+7 more
wiley +1 more source
circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes [PDF]
Objective This study investigated the effects of circRNA18_46222157_46248185 (named circRNA18) on goat melanogenesis, which differs significantly in goat skins isolated from white and brown coat-colored skins.
Kai Yuan Ji+5 more
doaj +1 more source