Results 231 to 240 of about 48,156 (309)
A skin explant model for studying UV‐induced DNA damage and repair
The study describes an ex vivo skin model that preserves the natural physiology of the skin while addressing ethical concerns related to animal research. We demonstrate this model maintains key characteristics and physiological responses of in vivo skin during short incubation periods. Moreover, this model requires fewer mice than in vivo testing, thus
Hailey Payne+3 more
wiley +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal+3 more
wiley +1 more source
Mapping the locus for ocular melanosis in Cairn Terriers
Abstract Objective To map the disease locus for familial ocular melanosis (OM) in the Cairn Terrier. Animals Studied Cairn Terriers with OM and normal control dogs. Procedure A genome‐wide association study (GWAS) was performed using 63 OM‐affected and 31 control Cairn Terriers, followed by haplotype analysis.
Paige A. Winkler+5 more
wiley +1 more source
ABSTRACT Objective To determine the frequency and clinical characteristics of local ocular adverse reactions to topical ophthalmic cidofovir administration in cats with presumptive feline herpesvirus‐1 (FHV‐1) keratoconjunctivitis. Animal Studied In total, 140 cats treated with cidofovir.
Eric C. Ledbetter, Amy J. Morgan
wiley +1 more source
Circular Dichroism of Active Fragments of α-Melanocyte-stimulating Hormone
Kiyoshi Ikeda+4 more
openalex +2 more sources
Glial cells in the heart: Implications for their roles in health and disease
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya+2 more
wiley +1 more source
Models of cardiomyocyte–non‐myocyte electrical interactions
Abstract figure legend Cardiomyocyte–non‐myocyte (CM–NM) electrotonic coupling. Left: conceptual contact‐based interactions between CM and other NM via connexin (Cx) proteins. Three basic scenarios are proposed: (i) ‘zero‐sided coupling’ where there are no electrical connections between CM and NM, (ii) ‘single‐sided coupling’ where NM are connected to ...
Ana Simon‐Chica+2 more
wiley +1 more source
GNA11 brain somatic pathogenic variant in an individual with phacomatosis pigmentovascularis [PDF]
al., et+2 more
core +1 more source