Results 1 to 10 of about 552,068 (289)

The effect of COVID-19 emergency in the management of melanoma in Italy

Dermatology Reports, 2021
The COVID-19 pandemic has severely hampered the functioning of any health system, absorbing a considerable amount of resources and with the threat of widespread infection in the health services.
Intergruppo Melanoma Italiano
doaj   +1 more source

Cross-platform comparison of immune signatures in immunotherapy-treated patients with advanced melanoma using a rank-based scoring approach

Journal of Translational Medicine, 2023
Background Gene expression profiling is increasingly being utilised as a diagnostic, prognostic and predictive tool for managing cancer patients. Single-sample scoring approach has been developed to alleviate instability of signature scores due to ...
Yizhe Mao, Tuba N. Gide, Nurudeen A. Adegoke, Camelia Quek, Nigel Maher, Alison Potter, Ellis Patrick, Robyn P. M. Saw, John F. Thompson, Andrew J. Spillane, Kerwin F. Shannon, Matteo S. Carlino, Serigne N. Lo, Alexander M. Menzies, Inês Pires da Silva, Georgina V. Long, Richard A. Scolyer, James S. Wilmott   +17 more
doaj   +1 more source

11 | Challenges in developing a digital pathology consultation network: insights from the MELCAYA experience

Dermatology Reports
Background: The increasing adoption of Whole Slide Image (WSI) technology has created new opportunities for collaboration in diagnostic pathology. This study aims to describe the development, implementation, and challenges of establishing a second ...
Italian Melanoma Intergroup
doaj   +1 more source

10 | Prognostic value of trans epidermal water loss in the treatment of actinic keratoses. A comparison amongst topical therapies for field cancerization

Dermatology Reports
Background: Actinic keratoses (AKs) are one of the most common premalignant skin conditions in the overall population. AKs are considered early precursors that may occasionally progress to squamous cell carcinoma.
Italian Melanoma Intergroup
doaj   +1 more source

16 | Sentinel lymph node biopsy in elderly patients with melanoma: prognostic value and impact on recurrence

Dermatology Reports
Background: The role of sentinel lymph node biopsy (SLNB) in elderly patients affected by cutaneous melanoma (CM) remains debated due to comorbidities, surgical risks and especially given the lower SLN positivity rates.
Italian Melanoma Intergroup
doaj   +1 more source

34 | Dissecting the spectrum of rare BRAF mutations in melanoma: a nation-wide study by the Italian Melanoma Intergroup

Dermatology Reports
Introduction: Non-V600E/K BRAF mutations have been reported in melanoma, but data on their clinical relevance are conflicting. This study investigated the distribution, prognostic role and functional impact of rare BRAF mutations in melanoma.
Italian Melanoma Intergroup
doaj   +1 more source

33 | A single center, real world experience with hedgehog pathway inhibitors in advanced basal cell carcinoma

Dermatology Reports
Background: Cutaneous basal cell carcinoma (cBCC) is the most common non melanocytic skin cancer, with a worldwide increased incidence. Basal cell carcinomas are heterogeneous, ranging from superficial or nodular lesions with a good prognosis to ...
Italian Melanoma Intergroup
doaj   +1 more source

25 | A phase II, open-label study to improve compliance and time of treatment after obtaining complete response through a tailored schedule of sonidegib in locally advanced basal cell carcinomas – the SONIBEC trial

Dermatology Reports
Background: Sonidegib is an effective treatment for laBCC, but it is associated with a risk of treatment-related adverse events (TRAEs), causing treatment discontinuation.
Italian Melanoma Intergroup
doaj   +1 more source

01 | End-of-life care in advanced melanoma and other skin cancers: a retrospective cohort from an italian comprehensive cancer center

Dermatology Reports
Background: Despite improvements in overall survival (OS) with immune-checkpoint inhibitors (ICIs) and targeted therapies, many patients with advanced melanoma or non-melanoma skin cancer (NMSC) still experience disease progression (PD) and remain on ...
Italian Melanoma Intergroup
doaj   +3 more sources

29 | The extracellular vesicle potential for the early detection of resistance to immunotherapy in melanoma patients

Dermatology Reports
Background: Although immunotherapy has revolutionized melanoma management, there is an urgent need to find useful biomarkers to follow disease evolution and response to therapy.
Italian Melanoma Intergroup
doaj   +1 more source